Department of Respiratory Medicine, Tobata General Hospital, 1-3-33, Fukuryugi, Tobata-Ku, Kitakyushu-City, Fukuoka, 804-0025, Japan.
Department of Respiratory Medicine, University of Occupational and Environmental Health, Japan, 1-1 Iseigaoka, Yahatanishi-Ku, Kitakyushu-City, Fukuoka, 807-8555, Japan.
BMC Pulm Med. 2023 Sep 30;23(1):365. doi: 10.1186/s12890-023-02668-1.
Smoking cessation is the most important intervention in chronic obstructive pulmonary disease (COPD), asthma, and asthma-COPD overlap (ACO); however, high rates of current cigarette smoking are observed in adults with these respiratory diseases. Meanwhile, rapidly increasing use of heated tobacco products (HTPs) is observed in Japan; however, the status of HTPs use has not been fully understood in adults with COPD, asthma, and ACO. This study aimed to reveal the association between COPD, asthma, and ACO and HTPs use in adults.
Data on Japanese individuals ≥ 40 years old obtained from the Japan Society and New Tobacco Internet Survey were analyzed. The prevalence of HTPs use in adults with COPD, asthma, and ACO, among individuals categorized into three groups according to cigarette smoking (never, former, and current), was calculated and the relationship between each disease and HTPs use were evaluated. The clinical diagnosis of these diseases was based on the self-reported diagnosis, as obtained from questionnaires.
A total of 19,308 individuals were included. The proportions of never, past, and current cigarettes smokers were 10,900 (56.5%), 4,903 (25.4%), and 3,505 (18.2%), respectively, and that of HTPs use was 1,813 (9.4%). In current cigarettes smokers, the adjusted odds ratios (ORs) of HTPs use was 2.88 (95% CI [confidence interval], 1.86-4.47), 1.23 (95% CI, 0.99-1.52), and 5.81 (95% CI, 3.12-10.82) in adults with COPD, asthma, and ACO compared to those without these respiratory diseases, respectively. Meanwhile, in past cigarettes smokers, the adjusted ORs of HTPs use was 0.51 (95% CI, 0.24-1.08), 0.69 (95% CI, 0.53-0.88), and 0.25 (95% CI, 0.06-1.07) in adults with COPD, asthma, and ACO, respectively.
HTPs use is more prevalent among current cigarettes smokers with COPD, asthma, and ACO compared to those without these respiratory diseases. Complete cessation of smoking both cigarettes and HTPs is the only way to achieve complete smoking cessation, therefore, adults with COPD, asthma, and ACO need to make greater efforts to quit smoking.
戒烟是慢性阻塞性肺疾病（COPD）、哮喘和哮喘-COPD 重叠（ACO）的最重要干预措施；然而，患有这些呼吸系统疾病的成年人中，目前吸烟率仍然很高。同时，在日本，加热烟草制品（HTP）的使用呈快速增长趋势；然而，COPD、哮喘和 ACO 患者对 HTP 使用的状况尚未得到充分了解。本研究旨在揭示 COPD、哮喘和 ACO 与成年人使用 HTP 之间的关联。
分析了来自日本社会和新烟草互联网调查的≥40 岁日本个体的数据。根据吸烟情况（从不吸烟、曾经吸烟和当前吸烟）将 COPD、哮喘和 ACO 成年患者分为三组，计算了 HTP 使用在三组患者中的流行率，并评估了每种疾病与 HTP 使用之间的关系。这些疾病的临床诊断基于问卷调查中自我报告的诊断。
共纳入 19308 名个体。从不吸烟者、过去吸烟者和当前吸烟者的比例分别为 10900 名（56.5%）、4903 名（25.4%）和 3505 名（18.2%），HTP 使用比例为 1813 名（9.4%）。在当前吸烟者中，与无这些呼吸系统疾病的成年人相比，COPD、哮喘和 ACO 成年患者使用 HTP 的调整比值比（OR）分别为 2.88（95%CI[置信区间]，1.86-4.47）、1.23（95%CI，0.99-1.52）和 5.81（95%CI，3.12-10.82）。而在过去吸烟者中，与无这些呼吸系统疾病的成年人相比，COPD、哮喘和 ACO 成年患者使用 HTP 的调整 OR 分别为 0.51（95%CI，0.24-1.08）、0.69（95%CI，0.53-0.88）和 0.25（95%CI，0.06-1.07）。
与无这些呼吸系统疾病的成年人相比，COPD、哮喘和 ACO 成年患者中当前吸烟者使用 HTP 的情况更为普遍。完全停止吸烟，包括香烟和 HTP，是实现完全戒烟的唯一途径，因此，COPD、哮喘和 ACO 成年患者需要更加努力地戒烟。
