Ornos Eric David, Murillo Karl Jeffrey, Ong Janus P
College of Medicine, University of the Philippines Manila, Taft Avenue, Manila, Philippines.
Division of Gastroenterology, Department of Medicine, University of the Philippines-Philippine General Hospital, Taft Avenue, Manila, Philippines.
Ann Hepatol. 2023 May-Jun;28(3):101085. doi: 10.1016/j.aohep.2023.101085. Epub 2023 Mar 6.
Liver diseases are a major cause of morbidity and mortality globally. In the Philippines, a lower middle-income country in Southeast Asia, liver diseases accounted for 27.3 cases per 1000 deaths. In this review, we discussed the prevalence, risk factors, and management of hepatitis B, hepatitis C and other viral hepatitis, non-alcoholic fatty liver disease, alcohol-associated liver disease, liver cirrhosis, and hepatocellular carcinoma. The true burden of liver disease in the Philippines is likely underestimated due to limited epidemiological studies. Thus, surveillance of liver disease should be strengthened. Clinical practice guidelines tailored to the local needs of the country have been developed for important liver diseases. Multisectoral cooperation among different stakeholders is needed to manage the burden of liver disease in the Philippines.
肝脏疾病是全球发病和死亡的主要原因。在东南亚的低收入中等国家菲律宾，肝脏疾病占每1000例死亡中的27.3例。在本综述中，我们讨论了乙型肝炎、丙型肝炎和其他病毒性肝炎、非酒精性脂肪性肝病、酒精性肝病、肝硬化和肝细胞癌的患病率、危险因素及管理。由于流行病学研究有限，菲律宾肝脏疾病的实际负担可能被低估。因此，应加强肝脏疾病监测。针对该国当地需求制定了重要肝脏疾病的临床实践指南。需要不同利益相关者之间开展多部门合作以应对菲律宾的肝脏疾病负担。
