Zhang Wenjun, Wang Li, Sun Jiwei, Cui Linlin, Zhang Haobo, Hu Jingmei
Center for Reproductive Medicine, Cheeloo College of Medicine, Shandong University, 250012, Jinan, Shandong, China.
Key laboratory of Reproductive Endocrinology of Ministry of Education, Shandong University, 250012, Jinan, Shandong, China.
Basic Clin Androl. 2023 Mar 9;33(1):4. doi: 10.1186/s12610-022-00180-w.
Coronavirus disease 2019 (COVID-19) has spread rapidly worldwide since its discovery in December 2019. Research published since the COVID-19 outbreak has focused on whether semen quality and reproductive hormone levels are affected by COVID-19. However, there is limited evidence on semen quality of uninfected men. This study aimed to compare semen parameters among uninfected Chinese sperm donors before and after the COVID-19 pandemic to determine the impact of the COVID-19 pandemic-related stress and lifestyle changes on uninfected men.
All semen parameters were non-significant except semen volume. The average age of sperm donors was higher after the COVID-19 (all P < 0.05). The average age of qualified sperm donors increased from 25.9 (SD: 5.3) to 27.6 (SD: 6.0) years. Before the COVID-19, 45.0% qualified sperm donors were students, but after the COVID-19, 52.9% were physical laborers (P < 0.05). The proportion of qualified sperm donors with a college education dropped from 80.8 to 64.4% after the COVID-19 (P < 0.05).
Although the sociodemographic characteristics of sperm donors changed after the COVID-19 pandemic, no decline in semen quality was found. There is no concern about the quality of cryopreserved semen in human sperm banks after the COVID-19 pandemic.
2019年12月发现新型冠状病毒肺炎（COVID-19）以来，其已在全球迅速传播。自COVID-19疫情爆发以来发表的研究主要关注COVID-19是否会影响精液质量和生殖激素水平。然而，关于未感染男性精液质量的证据有限。本研究旨在比较COVID-19大流行前后未感染的中国精子捐献者的精液参数，以确定与COVID-19大流行相关的压力和生活方式变化对未感染男性的影响。
除精液量外，所有精液参数均无统计学意义。COVID-19之后精子捐献者的平均年龄更高（所有P < 0.05）。合格精子捐献者的平均年龄从25.9岁（标准差：5.3）增至27.6岁（标准差：6.0）。COVID-19之前，45.0%的合格精子捐献者为学生，但COVID-19之后，52.9%为体力劳动者（P < 0.05）。COVID-19之后，大学学历的合格精子捐献者比例从80.8%降至64.4%（P < 0.05）。
尽管COVID-19大流行后精子捐献者的社会人口学特征发生了变化，但未发现精液质量下降。COVID-19大流行后，无需担心人类精子库中冷冻精液的质量。
