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住院患者死亡率的昼夜节律:一项大型队列的回顾性观察。

Circadian aspects of mortality in hospitalized patients: A retrospective observation from a large cohort.

机构信息

Department of Neurology, Sichuan Academy of Medical Science & Sichuan Provincial People's Hospital, Chengdu, China.

Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, China.

出版信息

Nurs Open. 2023 Jul;10(7):4630-4636. doi: 10.1002/nop2.1711. Epub 2023 Mar 8.

DOI:10.1002/nop2.1711
PMID:36890609
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10277412/
Abstract

AIM

This study aimed to describe the circadian characteristics of hospitalized mortality in order to provide nursing guidance for preventing in-hospital mortality.

DESIGN

A retrospective analysis on inpatient information was implemented.

METHODS

Harmonic Analysis of Time Series was applied to quantify the periodic structure of the frequency of the occurrence of death.

RESULTS

A total of 3300 cases were included in the present study (male, 63.4% and median age 73 years), including 1540 (46.7%) ICU patients. Incidence of overall hospitalized death exhibited a circadian pattern, presenting peaks from 07:00 to 12:00 and 15:00 to 20:00 P.M., with 21.5% and 13.1% increase above the average at those peak points, respectively. Similarly, the incidence of sudden cardiac death (SCD) showed peaks between 06:00-12:00 and 15:00-20:00, with a 34.7% and 28.0% increase above the average at peak time, respectively. The distribution of death incidence revealed no statistical difference between SCD and non-SCD (p = 0.525).

摘要

目的

本研究旨在描述住院死亡率的昼夜节律特征,以便为预防住院死亡率提供护理指导。

设计

对住院患者信息进行回顾性分析。

方法

时间序列谐波分析用于量化死亡发生频率的周期性结构。

结果

本研究共纳入 3300 例病例(男性占 63.4%,中位年龄为 73 岁),包括 1540 例(46.7%)ICU 患者。总的住院死亡率呈现昼夜节律模式,在上午 7:00 至 12:00 和下午 15:00 至 20:00 出现峰值,分别比平均值高出 21.5%和 13.1%。同样,心源性猝死(SCD)的发生率在上午 6:00 至 12:00 和下午 15:00 至 20:00 之间出现峰值,分别比平均值高出 34.7%和 28.0%。死亡发生率的分布在 SCD 和非 SCD 之间没有统计学差异(p=0.525)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f03c/10277412/87e603ef43b1/NOP2-10-4630-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f03c/10277412/53fd679fdbf2/NOP2-10-4630-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f03c/10277412/f76bbf954776/NOP2-10-4630-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f03c/10277412/87e603ef43b1/NOP2-10-4630-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f03c/10277412/53fd679fdbf2/NOP2-10-4630-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f03c/10277412/f76bbf954776/NOP2-10-4630-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f03c/10277412/87e603ef43b1/NOP2-10-4630-g001.jpg

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