Shlopov V G, Shevchenko T I
Arkh Patol. 1987;49(9):32-8.
Comprehensive morphologic studies of material from postmortem examinations of 7 psoriatic patients (3 with progressive and 4 with stable psoriasis) indicated systemic progressive involvement of connective tissue and vessel walls--with development of proliferative and destructive vasculitis in the microcirculatory bed--as the underlying morphologic feature of the disease. Excessive epidermal proliferation was due to the damage sustained by basement membranes and to gross disorganization of the connective tissue and vessel walls, which compromised the collagen-mediated regulation of epithelium-mesenchyme interactions.
对7例银屑病患者（3例进行期和4例稳定期）尸体解剖材料进行的全面形态学研究表明，结缔组织和血管壁出现系统性进行性受累，微循环床出现增殖性和破坏性血管炎，这是该疾病潜在的形态学特征。表皮过度增殖是由于基底膜受到损伤以及结缔组织和血管壁严重紊乱，这损害了胶原蛋白介导的上皮-间充质相互作用的调节。
