Pantovic Milica, Djordjevic Ognjen, Radevic Svetlana, Bankovic Dragic, Ilic Katarina Parezanovic, Radovanovic Snezana
Clinical Hospital Center Zemun, Belgrade, Serbia.
Department of Hygiene and Ecology, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia.
Dermatol Pract Concept. 2023 Jan 1;13(1):e2023008. doi: 10.5826/dpc.1301a8.
Malignant melanoma is one of the rarest forms of skin cancer but it is the most deadly.
The objective of this paper was to analyze the epidemiological characteristics and trends of mortality from malignant melanoma in the population of Central Serbia in the period 1999-2015.
The study was designed as a retrospective descriptive epidemiological study. Standardized mortality rates were used in statistical data processing. A linear trend model and regression analysis were used to examine trends in malignant melanoma mortality.
In Serbia, malignant melanoma mortality shows an increasing trend. The overall age-adjusted melanoma death rate was 2.6 per 100,000 with a higher death rate among men (3.03 per 100,000) than among women (2.1 per 100,000). Malignant melanoma mortality rates increase with age in both sexes and are highest in the age group of 75 and older. The highest increase in mortality in men is recorded in the 65-69 age group, with an average percentage increase of 21.33 (95% CI, 8.40 - 51.05), while in women the largest increase in mortality was recorded in the 35-39 age group, with an average percentage increase of 31.4 and in the 70-74 age group, 12.9.
The trend of increasing mortality from malignant melanoma in Serbia is similar to those in most developed countries. Education and improvement of awareness in the general population and among health professionals are vital to reducing melanoma mortality in the future.
恶性黑色素瘤是最罕见的皮肤癌形式之一，但却是最致命的。
本文旨在分析1999 - 2015年期间塞尔维亚中部人群中恶性黑色素瘤的流行病学特征及死亡率趋势。
本研究设计为回顾性描述性流行病学研究。统计数据处理采用标准化死亡率。使用线性趋势模型和回归分析来检验恶性黑色素瘤死亡率的趋势。
在塞尔维亚，恶性黑色素瘤死亡率呈上升趋势。总体年龄调整后的黑色素瘤死亡率为每10万人2.6例，男性死亡率（每10万人3.03例）高于女性（每10万人2.1例）。男女两性的恶性黑色素瘤死亡率均随年龄增长而升高，在75岁及以上年龄组中最高。男性死亡率增长最高的年龄段为65 - 69岁，平均百分比增长为21.33（95%可信区间，8.40 - 51.05），而女性死亡率增长最大的年龄段为35 - 39岁，平均百分比增长为31.4，在70 - 74岁年龄组为12.9。
塞尔维亚恶性黑色素瘤死亡率上升趋势与大多数发达国家相似。对普通人群和卫生专业人员进行教育并提高其意识对于未来降低黑色素瘤死亡率至关重要。
