Tran Nguyen H N, Clayton Andrew H A
Optical Sciences Centre, Department of Physics and Astronomy, School of Science, Computing and Engineering Technologies, Swinburne University of Technology, Melbourne, Australia.
Phys Biol. 2023 Mar 29;20(3). doi: 10.1088/1478-3975/acc300.
Signal transduction networks are responsible for transferring biochemical signals from the extracellular to the intracellular environment. Understanding the dynamics of these networks helps understand their biological processes. Signals are often delivered in pulses and oscillations. Therefore, understanding the dynamics of these networks under pulsatile and periodic stimuli is useful. One tool to do this is the transfer function. This tutorial outlines the basic theory behind the transfer function approach and walks through some examples of simple signal transduction networks.
信号转导网络负责将生物化学信号从细胞外环境传递到细胞内环境。了解这些网络的动态有助于理解其生物学过程。信号通常以脉冲和振荡的形式传递。因此，了解这些网络在脉动和周期性刺激下的动态是有用的。实现这一点的一个工具是传递函数。本教程概述了传递函数方法背后的基本理论，并介绍了一些简单信号转导网络的示例。
