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社交距离措施对儿童上呼吸道感染有影响吗?一项观察性对照研究及简要文献回顾。

Does social distancing impact pediatric upper airway infections? An observational controlled study and a brief literature review.

机构信息

Department of Neuroscience DNS, Otolaryngology Section, University of Padova, Padova, Italy.

Department of Neuroscience DNS, Otolaryngology Section, University of Padova, Padova, Italy; Otorhinolaryngology Unit, AULSS5 Polesana, Rovigo, Italy.

出版信息

Am J Otolaryngol. 2023 May-Jun;44(3):103801. doi: 10.1016/j.amjoto.2023.103801. Epub 2023 Mar 1.

Abstract

PURPOSE

SARS-CoV-2 pandemic has reduced social interaction even among children. The objective of the study was to assess the role of social distancing in the course of common pediatric upper airway recurrent diseases.

MATERIALS AND METHODS

Patients aged ≤14 years with at least one ENT-related clinical condition were retrospectively recruited. All patients had two outpatient evaluations in the same period (April - September): the control group had the first evaluation in 2018 and second in 2019, whereas the case group had the first evaluation in 2019 and second in 2020. Patients of each group were individually compared between their two visits and deemed improved/unchanged/worsened for each specific ENT condition. The percentage of children improved/unchanged/worsened were then collectively compared between the two groups for each condition.

RESULTS

Patients who experienced social distancing presented a significantly higher improvement rate than controls for recurrent acute otitis media episodes (35.1 % vs. 10.8 %; Fisher's exact test p = 0.033) and for tympanogram type (54.5 % vs. 11.1 %, Fisher's exact test p = 0.009).

CONCLUSIONS

The anti-contagion social restrictions decreased the prevalence of middle ear infections and effusion in children. Further studies on larger cohorts are required to better elucidate these findings.

摘要

目的

SARS-CoV-2 大流行即使在儿童中也减少了社交互动。本研究的目的是评估社交距离在常见儿科上呼吸道复发性疾病中的作用。

材料和方法

回顾性招募了年龄≤14 岁且至少有一种耳鼻喉相关临床症状的患者。所有患者在同一时期(4 月至 9 月)接受了两次门诊评估:对照组在 2018 年进行了第一次评估,在 2019 年进行了第二次评估,而病例组在 2019 年进行了第一次评估,在 2020 年进行了第二次评估。对每组患者的两次就诊进行单独比较,并根据每个特定的耳鼻喉状况将其归类为改善/不变/恶化。然后将两组之间每种情况下改善/不变/恶化的儿童百分比进行集体比较。

结果

经历社交距离的患者与对照组相比,复发性急性中耳炎发作的改善率明显更高(35.1%比 10.8%;Fisher 确切检验 p=0.033),鼓室图类型的改善率也更高(54.5%比 11.1%,Fisher 确切检验 p=0.009)。

结论

抗传染病的社交限制降低了儿童中耳感染和积液的发生率。需要进一步研究更大的队列,以更好地阐明这些发现。

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