• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

掌长肌腱移植联合人羊膜和脂肪间充质干细胞修复指深屈肌腱I区长期功能预后评估:一例报告

Long term functional outcome evaluation in post flexor digitorum profundus tendon zone I rupture repaired by palmaris longus tendon grafting augmented with human amniotic membranes and adipose derived mesenchymal stem cell: A case report.

作者信息

Suroto Heri, Satmoko Benedictus Anindita, Rarasati Twindy, Prajasari Tabita

机构信息

Orthopedic and Traumatology Department, Faculty of Medicine, Airlangga University/Dr. Soetomo Academic General Hospital, Surabaya, Indonesia.

Faculty of Medicine, Gadjah Mada University, Yogyakarta, Indonesia.

出版信息

Int J Surg Case Rep. 2023 Mar;104:107960. doi: 10.1016/j.ijscr.2023.107960. Epub 2023 Mar 5.

DOI:10.1016/j.ijscr.2023.107960
PMID:36893703
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10018546/
Abstract

INTRODUCTION AND IMPORTANCE

The sport climbing has many complex maneuvers of the hand producing many potential injuries in flexor digitorum profundus tendon (FDPT). The late management due to an athlete high demand on competition makes the complication of retracted tendon and adhesion tend to occur. We provide the long terms functional outcome in FDPT zone I rupture repaired by palmaris longus (PL) tendon grafting augmented with human amniotic (hAM) and adipose derived mesenchymal stem cell (ASCs).

CASE PRESENTATION

We present a case of a 31-years old male sport climbing athlete with excruciating pain in the right middle finger due to an injury at distal phalangeal area occurred two months earlier. Intraoperatively, Bruner's incision was performed for exploration. A modified Kessler suture technique with running sutures around the sutured stump was used. We slightly overcorrected tension between PL and FDPT distal stumps. We shielded the distal and proximal sutured areas with hAM augmented with ASCs. The result was remarkable as he could return to competitive sport.

CLINICAL DISCUSSION

Zones I and II have a high adhesion risk due to their complex structures. In the case of the PL tendon graft, the sutured stump lies in these zones which can affect outcomes. An HAM augmented with ASCs has an anti-adhesive property that allows smooth gliding of the tendon FDPT on two sutured stump junctions, as well as stimulating the tendon to produce tenocytes, which accelerates tendon healing.

CONCLUSION

The combination of our technique and regenerative therapy effectively prevents adhesions and modulates tendon healing.

摘要

引言与重要性

竞技攀岩运动中手部有许多复杂动作,这会导致指深屈肌腱(FDPT)出现多种潜在损伤。由于运动员对比赛的高要求,后期治疗往往会导致肌腱回缩和粘连等并发症的发生。我们提供了采用掌长肌(PL)肌腱移植并辅以人羊膜(hAM)和脂肪间充质干细胞(ASCs)修复FDPT I区断裂的长期功能结果。

病例介绍

我们报告一例31岁男性竞技攀岩运动员,因两个月前远节指骨区域受伤,右手中指剧痛。术中采用布鲁纳切口进行探查。使用改良的凯斯勒缝合技术,在缝合残端周围进行连续缝合。我们对PL和FDPT远端残端之间的张力进行了轻微过度矫正。我们用含ASCs的hAM覆盖远端和近端缝合区域。结果非常显著,他能够重返竞技运动。

临床讨论

I区和II区因其结构复杂,粘连风险高。对于PL肌腱移植,缝合残端位于这些区域,这可能会影响治疗效果。含ASCs的hAM具有抗粘连特性,可使FDPT肌腱在两个缝合残端连接处顺利滑动,还能刺激肌腱产生成纤维细胞,加速肌腱愈合。

结论

我们的技术与再生疗法相结合可有效预防粘连并调节肌腱愈合。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0a8/10018546/c38b2e72d811/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0a8/10018546/5c0ca5328ff3/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0a8/10018546/d95b0cccbb48/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0a8/10018546/c3ed4a11c081/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0a8/10018546/6ae5b56023a3/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0a8/10018546/c38b2e72d811/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0a8/10018546/5c0ca5328ff3/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0a8/10018546/d95b0cccbb48/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0a8/10018546/c3ed4a11c081/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0a8/10018546/6ae5b56023a3/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0a8/10018546/c38b2e72d811/gr5.jpg

相似文献

1
Long term functional outcome evaluation in post flexor digitorum profundus tendon zone I rupture repaired by palmaris longus tendon grafting augmented with human amniotic membranes and adipose derived mesenchymal stem cell: A case report.掌长肌腱移植联合人羊膜和脂肪间充质干细胞修复指深屈肌腱I区长期功能预后评估:一例报告
Int J Surg Case Rep. 2023 Mar;104:107960. doi: 10.1016/j.ijscr.2023.107960. Epub 2023 Mar 5.
2
Closed Traumatic Zone 2 Flexor Tendon Injury of the Long Finger - A Case Report.闭合性 2 区创伤性屈指肌腱损伤 - 1 例报告。
J Hand Surg Asian Pac Vol. 2023 Feb;28(1):113-116. doi: 10.1142/S2424835523720013. Epub 2023 Feb 13.
3
[The Mantero technique for flexor tendon repair - an alternative?].[曼泰罗屈肌腱修复技术——一种替代方法?]
Handchir Mikrochir Plast Chir. 2003 Dec;35(6):363-7. doi: 10.1055/s-2003-44680.
4
Flexor Digitorum Superficialis Tendon Transfer for Wrist Extension.用于腕关节伸展的指浅屈肌腱转移术
JBJS Essent Surg Tech. 2021 Nov 8;11(4). doi: 10.2106/JBJS.ST.21.00011. eCollection 2021 Oct-Dec.
5
Spontaneous Midsubstance Rupture of the Flexor Digitorum Profundus Tendon of the Long Finger.示指指深屈肌腱自发性中间部断裂
J Hand Surg Glob Online. 2022 Jan 10;4(5):306-310. doi: 10.1016/j.jhsg.2021.12.007. eCollection 2022 Sep.
6
[Flexor digitorum (hallucis) longus muscle tendon transfer in the repair of old rupture of the Achilles tendon].[趾长(拇长)屈肌腱转移修复陈旧性跟腱断裂]
Zhongguo Gu Shang. 2008 Apr;21(4):297-9.
7
Flexor Tendon Grafting Using Extrasynovial Tendons Followed by Early Active Mobilization.使用滑膜外肌腱进行屈肌腱移植并早期主动活动
J Hand Surg Glob Online. 2020 Apr 18;2(3):159-165. doi: 10.1016/j.jhsg.2020.03.005. eCollection 2020 May.
8
Z-plasty lengthening of the flexor digitorum profundus at the wrist (zone 5) for the treatment of jersey finger: anatomical study and evaluation of advancement obtained.腕部(5区)指深屈肌腱Z形延长术治疗“篮球指”:解剖学研究及所获延长效果评估
J Plast Reconstr Aesthet Surg. 2014 Aug;67(8):e189-94. doi: 10.1016/j.bjps.2014.04.025. Epub 2014 May 13.
9
Resection of the flexor digitorum superficialis reduces gliding resistance after zone II flexor digitorum profundus repair in vitro.在体外,切除指浅屈肌可降低II区指深屈肌修复后的滑动阻力。
J Hand Surg Am. 2002 Mar;27(2):316-21. doi: 10.1053/jhsu.2002.31729.
10
Clinical outcomes of zone II flexor tendon repair depending on mechanism of injury.根据损伤机制的Ⅱ区屈指肌腱修复的临床结果
J Hand Surg Am. 2012 Dec;37(12):2532-40. doi: 10.1016/j.jhsa.2012.09.021.

引用本文的文献

1
State-of the-art and future perspective in co-culture systems for tendon engineering.用于肌腱工程的共培养系统的现状与未来展望。
Biomater Biosyst. 2025 Mar 5;17:100110. doi: 10.1016/j.bbiosy.2025.100110. eCollection 2025 Mar.

本文引用的文献

1
Applications of Human Amniotic Membrane for Tissue Engineering.人羊膜在组织工程中的应用。
Membranes (Basel). 2021 May 25;11(6):387. doi: 10.3390/membranes11060387.
2
The SCARE 2020 Guideline: Updating Consensus Surgical CAse REport (SCARE) Guidelines.SCARE 2020 指南:更新共识手术病例报告(SCARE)指南。
Int J Surg. 2020 Dec;84:226-230. doi: 10.1016/j.ijsu.2020.10.034. Epub 2020 Nov 9.
3
Flexor tendon repair with amniotic membrane.羊膜修复屈肌腱。
Int Orthop. 2020 Oct;44(10):2037-2045. doi: 10.1007/s00264-020-04752-1. Epub 2020 Aug 4.
4
Adipose-derived stem cells improve tendon repair and prevent ectopic ossification in tendinopathy by inhibiting inflammation and inducing neovascularization in the early stage of tendon healing.脂肪来源干细胞通过在肌腱愈合早期抑制炎症和诱导新血管形成,改善肌腱修复并预防肌腱病中的异位骨化。
Regen Ther. 2020 Jan 17;14:103-110. doi: 10.1016/j.reth.2019.12.003. eCollection 2020 Jun.
5
Flexor tendon injuries.屈肌腱损伤
J Clin Orthop Trauma. 2019 Sep-Oct;10(5):853-861. doi: 10.1016/j.jcot.2019.08.005. Epub 2019 Aug 19.
6
Therapeutic Mechanisms of Human Adipose-Derived Mesenchymal Stem Cells in a Rat Tendon Injury Model.人脂肪间充质干细胞在大鼠肌腱损伤模型中的治疗机制
Am J Sports Med. 2017 May;45(6):1429-1439. doi: 10.1177/0363546517689874. Epub 2017 Mar 14.
7
The effect of mesenchymal stromal cell sheets on the inflammatory stage of flexor tendon healing.间充质基质细胞片对屈肌腱愈合炎症阶段的影响。
Stem Cell Res Ther. 2016 Sep 27;7(1):144. doi: 10.1186/s13287-016-0406-0.
8
The flexor tendon pulley system and rock climbing.屈肌腱滑车系统与攀岩
J Hand Microsurg. 2012 Jun;4(1):25-9. doi: 10.1007/s12593-012-0061-3. Epub 2012 Jan 18.
9
Zone 2 flexor tendon injuries: Venturing into the no man's land.2区屈肌腱损伤:踏入无人区。
Indian J Orthop. 2012 Nov;46(6):608-15. doi: 10.4103/0019-5413.104183.
10
An overview of the management of flexor tendon injuries.屈指肌腱损伤的治疗概述。
Open Orthop J. 2012;6:28-35. doi: 10.2174/1874325001206010028. Epub 2012 Feb 23.