Division of Infectious Diseases, Department of Medicine, Renaissance School of Medicine, Stony Brook University, 101 Nicolls Road, HSC 15-060I, Stony Brook, NY 11794, USA; Center for Infectious Diseases, Department of Microbiology and Immunology, Stony Brook University, 101 Nicolls Road, HSC 15-060I, Stony Brook, NY 11794, USA.
Division of Infectious Diseases, Department of Medicine, Renaissance School of Medicine, Stony Brook University, 101 Nicolls Road, HSC 15-060I, Stony Brook, NY 11794, USA; Center for Infectious Diseases, Department of Microbiology and Immunology, Stony Brook University, 101 Nicolls Road, HSC 15-060I, Stony Brook, NY 11794, USA.
Cell Host Microbe. 2023 Mar 8;31(3):329-330. doi: 10.1016/j.chom.2023.02.003.
Recently in Nature Medicine, Musvosvi et al. analyzed single-cell T cell receptor (TCR) sequencing by grouping of lymphocyte interactions by paratope hotspots (GLIPH2) in a South African longitudinal cohort at high risk for tuberculosis. They find peptide antigen-specific T cells correlating with control of primary infection, potentially informing future vaccines.
最近，在《自然医学》杂志上，Musvosvi 等人分析了南非纵向队列中高结核病风险人群的淋巴细胞相互作用通过表位热点（GLIPH2）分组的单细胞 T 细胞受体（TCR）测序。他们发现与原发性感染控制相关的肽抗原特异性 T 细胞，这可能为未来的疫苗提供信息。
