National Hospital Kandy, Kandy, Sri Lanka.
Department of Community Medicine, Faculty of Medicine and Allied Sciences, Rajarata University of Sri Lanka, Saliyapura, 50008, Sri Lanka.
Spinal Cord Ser Cases. 2023 Mar 9;9(1):7. doi: 10.1038/s41394-023-00565-7.
The occurrence of concurrent hypertrophied posterior longitudinal ligament (HPLL) and hypertrophied ligamentum flavum (HLF) in the thoracic spine is a very rare presentation. This case report describes a young female who developed thoracic myelopathy secondary to a combination of both thoracic HPLL and HLF.
A 30-year-old previously well female was referred for an MRI scan of the thoraco-lumbar spine. She was having lower limb weakness and difficulty in walking, which had progressed over 3 months. On examination, she was found to have spastic lower limbs with associated motor weakness. Her biochemical investigations were unremarkable. The MRI scan showed HPLL, which was uniformly hypointense on T2W images and was isointense on T1W images. The hypertrophied segment was extending from T2 level to T7 level. Similarly, the ligamentum flavum was hypertrophied from T1 level to T8 level. The thoracic spinal cord was seen compressed between the hypertrophied ligaments. The compressed cord showed central hyperintense signal pattern in T2W images. CT scan of the thoracic spine did not show any calcifications or ossifications along the ligaments. Patient underwent posterior decompressive surgery and she had an uneventful recovery.
Although few cases of HPLL and HLF were reported in older patients in literature, both these conditions were found in this patient at a younger age. HPLL and HLF are thought to be precursors of ossification of these ligaments and these patients need long-term follow-up.
胸椎并发后纵韧带肥厚(HPLL)和黄韧带肥厚(HLF)非常罕见。本病例报告描述了一位年轻女性,因同时存在胸椎 HPLL 和 HLF 而导致胸段脊髓病。
一位 30 岁既往健康的女性因胸腰椎 MRI 检查被转介。她出现下肢无力和行走困难,症状已持续 3 个月。体格检查发现下肢痉挛,伴有运动无力。她的生化检查无明显异常。MRI 显示 HPLL,T2W 图像呈均匀低信号,T1W 图像呈等信号。肥厚段从 T2 水平延伸至 T7 水平。同样,黄韧带从 T1 水平延伸至 T8 水平。胸椎脊髓被增厚的韧带压迫。受压的脊髓在 T2W 图像上显示中央高信号模式。胸椎 CT 扫描未显示韧带处有任何钙化或骨化。患者接受了后路减压手术,恢复顺利。
虽然文献中有少数 HPLL 和 HLF 发生在老年患者的报道,但在这位年轻患者中同时存在这两种情况。HPLL 和 HLF 被认为是这些韧带骨化的前兆,这些患者需要长期随访。