Department of Plastic Surgery, Xijing Hospital, Air Force Medical University, Xi'an, Shaanxi Province, China.
Cell Tissue Bank. 2023 Dec;24(4):705-710. doi: 10.1007/s10561-023-10083-3. Epub 2023 Mar 10.
The repair of bone explore wounds is one of the difficult problems in plastic and reconstruction surgery. Platelet-rich plasma (PRP) is a safe and efficient therapeutic option for various trauma, including Osteoarticular, musculoskeletal, and Wound injuries. However, the preparation and storage of PRP becomes challenging for patients with poor systemic status and requiring multi-use of PRP. The availability of safe, reliable tissue bank makes it possible. We report a case of a 42-year-old woman patient with a chronic hip wound combined with ischium bone exploration. And the patient who was treated with long-term glucocorticoids for rheumatoid arthritis has been through the experience of extensive conservative management. Thereafter necrosectomy and Vacuum-Assisted Closure (VAC) surgical procedure failed, and a PRP daily injection was performed at the ischial muscle and soft tissue. Neo-muscle appeared around the explored ischium bone after 8 weeks of injection and Complete wound healing was obtained in 3 months.
骨创伤的修复是整形和重建外科的难题之一。富含血小板的血浆（PRP）是一种安全有效的治疗方法，可用于多种创伤，包括骨关节、肌肉骨骼和创伤。然而，对于全身状况不佳且需要多次使用 PRP 的患者，PRP 的制备和储存变得具有挑战性。安全可靠的组织库的可用性使其成为可能。我们报告了一例 42 岁女性慢性髋部创伤合并坐骨骨探索的病例。该患者因类风湿性关节炎长期接受糖皮质激素治疗，曾经历广泛的保守治疗。此后，坏死切除术和负压封闭（VAC）手术失败，在坐骨肌肉和软组织中每天注射 PRP。注射 8 周后，探索性坐骨骨周围出现新肌肉，3 个月后完全愈合。
