School of Medicine, Guilan University of Medical Sciences (GUMS), Rasht, Guilan Province, Iran.
Roud Trauma Research Center, Guilan University of Medical Sciences, Rasht, Iran.
J Med Case Rep. 2023 Mar 10;17(1):88. doi: 10.1186/s13256-023-03824-1.
In December 2019, coronavirus disease 2019 spread worldwide, causing acute respiratory distress syndrome. Coronavirus disease 2019 presents from an asymptomatic infection to severe disease causing multiorgan failure. Neurological manifestations were observed in some patients, including intracerebral hemorrhage. Bilateral basal ganglia hemorrhage is rare due to trauma.
Our patient was a 14-year-old Iranian boy with multiple trauma and loss of consciousness who tested positive for coronavirus disease 2019. The brain computed tomography scan reported bilateral basal ganglia hemorrhage. Bilateral ground glass opacity was reported through a chest computed tomography scan.
In this study, we reported a 14-year-old boy referred to the emergency room due to multiple trauma. Through the medical interventions, bilateral basal ganglia hemorrhage was discovered incidentally. Coronavirus disease 2019 was detected in this patient on the basis of findings in chest computed tomography scan and positive real reverse transcription polymerase chain reaction test. Several clinical reports and series exploring the relationship between coronavirus disease 2019 and ischemic strokes have been published. Coronavirus disease 2019, like other acute respiratory syndromes, can invade the central nervous system through hematogenous and neuronal dissemination or it can be an immune response to the cytokine storm. In conclusion, it is vital to know the pathophysiology of the neurological manifestations of coronavirus disease 2019 and prevent the mild neurological manifestations leading to severe conditions.
2019 年 12 月，新型冠状病毒病（COVID-19）在全球范围内传播，导致急性呼吸窘迫综合征。COVID-19 从轻症无症状感染到重症导致多器官衰竭。一些患者出现了神经系统表现，包括脑出血。由于创伤，双侧基底节区出血很少见。
我们的患者是一名 14 岁的伊朗男孩，有多处创伤和意识丧失，COVID-19 检测呈阳性。脑部计算机断层扫描报告双侧基底节区出血。胸部计算机断层扫描报告双侧磨玻璃影。
在本研究中，我们报告了一名 14 岁男孩因多处创伤被送往急诊室。通过医疗干预，意外发现双侧基底节区出血。根据胸部计算机断层扫描和阳性实时逆转录聚合酶链反应检测结果，该患者被诊断为 COVID-19。已经发表了一些关于 COVID-19 与缺血性中风之间关系的临床报告和系列研究。COVID-19 与其他急性呼吸道综合征一样，可通过血源性和神经元传播侵犯中枢神经系统，也可作为细胞因子风暴的免疫反应。总之，了解 COVID-19 的神经表现的病理生理学并预防轻度神经表现导致严重情况至关重要。
