El-Sherbiny Hossam R, El-Shalofy Amr S, Samir Haney
Theriogenology Department, Faculty of Veterinary Medicine, Cairo University, Giza, 12211, Egypt.
Ir Vet J. 2023 Mar 9;76(1):7. doi: 10.1186/s13620-023-00235-y.
Higher body fatness adversely affects metabolic and hormonal homeostasis. The present work aimed to evaluate the association between body condition score (BCS) and haemodynamic pattern and echogenic appearence of the testes as well as nitric oxide (NO) levels and total antioxidant capacity (TAC). For that, fifteen Ossimi rams were blocked according to their BCS into a lower BCS group (L-BCS:2-2.5; n = 5), medium BCS group (M-BCS:3-3.5; n = 5), and higher BCS group (H-BCS:4-4.5; n = 5). Rams were examined for testicular haemodynamics (TH; Doppler ultrasonography), testicular echotexture (TE; B-mode image software analysis), and serum levels of NO and TAC (colorimetric). Results are presented as means ± standard error of the mean. There was a significant (P < 0.05) difference in the resistive index and pulsatility index means among the groups under experimentation, being the least in the L-BCS group (0.43 ± 0.02 and 0.57 ± 0.04, respectively) compared to the M-BCS (0.53 ± 0.03 and 0.77 ± 0.03, respectively) and H-BCS rams (0.57 ± 0.01 and 0.86 ± 0.03, respectively). Among blood flow velocity measurements [peak systolic, end-diastolic (EDV), and time-average maximum], only EDV showed significant (P < 0.05) higher values in the L-BCS group (17.06 ± 1.03 cm/s) compared to M-BCS (12.58 ± 0.67 cm/s) and H-BCS (12.51 ± 0.61 cm/s) groups. Regarding the TE results, there were no significant differences among the examined groups. There were significant differences (P < 0.01) in the concentrations of TAC and NO among the groups under experimentation, in which the L-BCS rams had the highest levels of TAC and NO in their sera (0.90 ± 0.05 mM/L and 62.06 ± 2.72 μM/L, respectively) than the M-BCS (0.058 ± 0.05 mM/L and 47.89 ± 1.49 μM/L, respectively) and H-BCS rams (0.45 ± 0.03 mM/L and 49.93 ± 3.63 μM/L, respectively). In conclusion, body condition score is associated with both testicular hemodynamic and the antioxidant capacity in rams.
较高的体脂会对代谢和激素稳态产生不利影响。本研究旨在评估体况评分（BCS）与血流动力学模式、睾丸回声外观以及一氧化氮（NO）水平和总抗氧化能力（TAC）之间的关联。为此，将15只奥西米公羊根据其BCS分为低BCS组（L-BCS：2-2.5；n = 5）、中BCS组（M-BCS：3-3.5；n = 5）和高BCS组（H-BCS：4-4.5；n = 5）。对公羊进行睾丸血流动力学（TH；多普勒超声检查）、睾丸回声纹理（TE；B模式图像软件分析）以及血清NO和TAC水平（比色法）检测。结果以平均值±平均标准误差表示。在实验中的各组之间，阻力指数和搏动指数平均值存在显著（P < 0.05）差异，与M-BCS组（分别为0.53±0.03和0.77±0.03）和H-BCS公羊（分别为0.57±0.01和0.86±0.03）相比，L-BCS组最低（分别为0.43±0.02和0.57±0.04）。在血流速度测量值[收缩期峰值、舒张末期（EDV）和时间平均最大值]中，与M-BCS组（12.58±0.67 cm/s）和H-BCS组（12.51±0.61 cm/s）相比，只有EDV在L-BCS组中显示出显著（P < 0.05）更高的值（17.06±1.03 cm/s）。关于TE结果，在各检测组之间没有显著差异。在实验中的各组之间，TAC和NO浓度存在显著差异（P < 0.01），其中L-BCS公羊血清中TAC和NO水平最高（分别为0.90±0.05 mM/L和62.06±2.72 μM/L），高于M-BCS组（分别为0.058±0.05 mM/L和47.89±1.49 μM/L）和H-BCS公羊（分别为0.45±0.03 mM/L和49.93±3.63 μM/L）。总之，体况评分与公羊的睾丸血流动力学和抗氧化能力均相关。
