Javid Farideh A, Waheed Fadi Abdul, Zainab Nisa, Khan Hamza, Amin Ibrahim, Bham Ammar, Ghoghawala Mohammed, Sheraz Aneem, Haloub Radi
Department of Pharmacy, University of Huddersfield, Huddersfield, HD1 3DH, UK.
Biotech and Pharmaceutical Management, Global Business School for Health (GBSH), University College London (UCL), London, UK.
J Pharm Policy Pract. 2023 Mar 9;16(1):42. doi: 10.1186/s40545-023-00546-z.
Attempts were made to review the literature on diabetic patients who experience complications when they contract COVID-19, and to determine whether ethnicity and other risk factors play an important role in the development of symptoms and their severity, as well as responding to medications. A literature search was performed using five keywords, namely COVID-19, diabetes, ethnicity, medications, and risk factors between January 2019 and December 2020 using electronic databases such as PubMed, Science Direct, Google Scholar, Springer Link, and Scopus. Forty studies were included. The review indicated that diabetes was a significant risk factor for poorer outcomes and increased mortality associated with COVID-19. There were several risk factors for diabetic patients that increased their likelihood of poorer outcomes associated with COVID-19. These included black and Asian ethnicity, male sex with high BMI. In conclusion, patients with diabetes of black or Asian origin with high BMI, male sex, and older age had an increased risk of poorer outcomes associated with COVID-19. This highlights the importance of considering the history of the patient in prioritising care and treatment.
本研究旨在回顾有关糖尿病患者感染新冠病毒(COVID-19)后出现并发症的文献,并确定种族和其他风险因素在症状发生、严重程度以及药物反应方面是否起重要作用。使用电子数据库(如PubMed、Science Direct、谷歌学术、Springer Link和Scopus),在2019年1月至2020年12月期间,使用五个关键词(即COVID-19、糖尿病、种族、药物和风险因素)进行文献检索。共纳入40项研究。综述表明,糖尿病是与COVID-19相关的预后较差和死亡率增加的重要风险因素。糖尿病患者存在多种风险因素,增加了与COVID-19相关的不良预后可能性。这些因素包括黑人及亚洲种族、高BMI男性。总之,高BMI、男性、年龄较大的黑人或亚洲裔糖尿病患者与COVID-19相关的不良预后风险增加。这凸显了在优先考虑护理和治疗时考虑患者病史的重要性。