Patel Tarika Deepak, Uzoaru Ikechukwu, Sutton Bradley P, Arnold Paul M
Department of Carle Illinois College of Medicine, University of Illinois Urbana-Champaign, Urbana, Illinois, United States.
Department of Pathology and Laboratory Medicine, Carle Foundation Hospital, Urbana, Illinois, United States.
Surg Neurol Int. 2023 Jan 27;14:35. doi: 10.25259/SNI_1167_2022. eCollection 2023.
Myeloid sarcoma is an uncommon malignant neoplasm that typically arises at extramedullary sites and is associated with a diagnosis of acute myeloid leukemia. While myeloid sarcoma can involve any organ, central nervous system involvement is rare, particularly in the adult population.
An 87-year-old female presented with progressive paraparesis of 5 days' duration. The magnetic resonance imaging (MRI) revealed an epidural tumor from T4 to T7 with cord compression. When she underwent a laminectomy for tumor resection, the pathology revealed a myeloid sarcoma with monocytic differentiation. Although she improved postoperatively, she elected to pursue hospice care and expired 4 months later.
Myeloid sarcoma is an uncommon malignant spinal neoplasm rarely seen in adults. For this 87-year-old female, MRI-documented cord compression warranted decompressive surgery. Although this patient did not opt for adjuvant therapy, other patients with such lesions may undergo additional chemotherapy or radiation therapy. Nevertheless, optimal management for such malignant tumor is still undefined.
髓系肉瘤是一种罕见的恶性肿瘤，通常发生于髓外部位，与急性髓系白血病的诊断相关。虽然髓系肉瘤可累及任何器官，但中枢神经系统受累罕见，尤其是在成人中。
一名87岁女性出现持续5天的进行性双下肢轻瘫。磁共振成像（MRI）显示胸4至胸7水平硬膜外肿瘤伴脊髓受压。当她接受椎板切除术以切除肿瘤时，病理显示为具有单核细胞分化的髓系肉瘤。尽管术后病情有所改善，但她选择接受临终关怀，4个月后去世。
髓系肉瘤是一种罕见的成人恶性脊柱肿瘤。对于这位87岁的女性，MRI记录的脊髓受压需要进行减压手术。虽然该患者未选择辅助治疗，但其他有此类病变的患者可能会接受额外的化疗或放疗。然而，这种恶性肿瘤的最佳治疗方案仍不明确。
