Fontes Benjamin, Scavone Danielle, Bridges Wesley, Landgraf Tessa, Fortgang Nanci
Yale Health, Environmental Health and Safety, Yale Center for Clinical Investigation, Yale University, New Haven, Connecticut, USA.
Appl Biosaf. 2023 Mar 1;28(1):32-42. doi: 10.1089/apb.2022.0018. Epub 2023 Mar 6.
Yale University designed and constructed a temporary field hospital for 100 COVID-19 symptomatic patients. Conservative biocontainment decisions were made in design and operational practices. Objectives of the field hospital included the safe flow of patients, staff, equipment and supplies, and obtaining approval by the Connecticut Department of Public Health (CT DPH) for opening as a field hospital.
The CT DPH regulations for mobile hospitals were used as primary guidance for the design, equipment, and protocols. References for BSL-3 and ABSL-3 design from the National Institutes of Health (NIH) and Tuberculosis isolation rooms from the United States Centers for Disease Control and Prevention (CDC) were also utilized. The final design involved an array of experts throughout the university.
Vendors tested and certified all High Efficiency Particulate Air (HEPA) filters and balanced the airflows inside the field hospital. Yale Facilities designed and constructed positive pressure access and exit tents within the field hospital, established appropriate pressure relationships between zones, and added Minimum Efficiency Reporting Value 16 exhaust filters. The BioQuell ProteQ Hydrogen Peroxide decontamination unit was validated with biological spores in the rear sealed section of the biowaste tent. A ClorDiSys Flashbox UV-C Disinfection Chamber was also validated. Visual indicators were placed the doors of the pressurized tents and spaced throughout the facility to verify airflows. The plans created to design, construct and operate the field hospital provide a blueprint for recreating and reopening a field hospital in the future if ever needed at Yale University.
耶鲁大学设计并建造了一家可容纳100名有新冠症状患者的临时野战医院。在设计和运营实践中做出了保守的生物安全防护决策。该野战医院的目标包括患者、工作人员、设备和物资的安全流通，以及获得康涅狄格州公共卫生部（CT DPH）作为野战医院开业的批准。
CT DPH关于移动医院的规定被用作设计、设备和方案的主要指导。还参考了美国国立卫生研究院（NIH）的生物安全三级（BSL-3）和动物生物安全三级（ABSL-3）设计，以及美国疾病控制与预防中心（CDC）的结核病隔离病房设计。最终设计涉及了全校的一系列专家。
供应商对所有高效空气过滤器（HEPA）进行了测试和认证，并平衡了野战医院内的气流。耶鲁设施部门在野战医院内设计并建造了正压进出帐篷，建立了各区域之间适当的压力关系，并增加了最低效率报告值为16的排气过滤器。BioQuell ProteQ过氧化氢消毒装置在生物废物帐篷的后部密封区域用生物孢子进行了验证。ClorDiSys Flashbox紫外线C消毒室也经过了验证。在加压帐篷的门上和整个设施内间隔设置了视觉指示器，以验证气流情况。为设计、建造和运营该野战医院而制定的计划为耶鲁大学未来在必要时重建和重新开放野战医院提供了蓝图。
