Fukuda Yasuko, Ochi Mikako, Kanazawa Ryouko, Nakajima Hiromu, Fukuo Keisuke, Nakai Masanobu
Department of Food Science and Nutrition, School of Human Environmental Science, Mukogawa Women's University, Ikebiraki-cho, Nishinomiya, Hyogo 663-8558, Japan.
Research Institute for Nutrition Science, Mukogawa Women's University, Ikebiraki-cho, Nishinomiya, Hyogo 663-8558, Japan.
J Clin Med Res. 2023 Feb;15(2):109-115. doi: 10.14740/jocmr4848. Epub 2023 Feb 28.
Differences in nutrition intake by meal intake time of geriatric patients may affect albumin (Alb) synthesis ability.
We included 36 geriatric patients (81.7 ± 7.7 years; 20 males and 16 females) as subjects. We calculated their dietary patterns (DPs) by computing intake by breakfast, lunch, and dinner, as well as by nutrient, for a weight of 1 kg/day for 4 weeks after hospitalization. We confirmed the relationship between "DP with a positive correlation with breakfast protein" and the change rate of albumin (Alb-RC). Then, we performed linear regression analysis to explore factors influencing Alb-RC and compared non-protein calorie/nitrogen ratio (NPC/N) between the upper and lower Alb-RC groups.
It was observed that Alb-RC was negatively correlated with "DP with a positive correlation with breakfast protein" (B = -0.055, P = 0.038) and positively correlated with breakfast NPC/N (B = 0.043, P = 0.029). Breakfast NPC/N tended to be higher in the upper group than in the lower group (P = 0.058).
The study revealed that there was a positive correlation between Alb-RC levels and breakfast NPC/N in geriatric patients at the care mix institution.
老年患者按进餐时间划分的营养摄入量差异可能会影响白蛋白（Alb）合成能力。
我们纳入了36名老年患者（81.7±7.7岁；男性20名，女性16名）作为研究对象。在患者住院后的4周内，我们通过计算早餐、午餐和晚餐的摄入量以及按营养素计算，得出他们的饮食模式（DPs），摄入量以每天每千克体重计算。我们确认了“与早餐蛋白质呈正相关的DP”与白蛋白变化率（Alb-RC）之间的关系。然后，我们进行线性回归分析以探究影响Alb-RC的因素，并比较了Alb-RC高低组之间的非蛋白质热量/氮比（NPC/N）。
观察到Alb-RC与“与早餐蛋白质呈正相关的DP”呈负相关（B=-0.055，P=0.038），与早餐NPC/N呈正相关（B=0.043，P=0.029）。较高Alb-RC组的早餐NPC/N往往高于较低组（P=0.058）。
该研究表明，在混合照护机构的老年患者中，Alb-RC水平与早餐NPC/N之间存在正相关。
