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重症监护肾脏病学中的床旁超声检查

POCUS in Intensive Care Nephrology.

作者信息

Connor-Schuler Randi, Suarez Jonathan

机构信息

Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Medicine, Emory University Atlanta, Georgia.

出版信息

POCUS J. 2022 Feb 1;7(Kidney):51-58. doi: 10.24908/pocus.v7iKidney.15016. eCollection 2022.

DOI:10.24908/pocus.v7iKidney.15016
PMID:36896116
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9994305/
Abstract

Acute kidney injury (AKI) is a significant problem for patients admitted to the intensive care unit (ICU), both due to the high incidence and associated mortality with rates of AKI requiring renal replacement therapy (RRT) of over 5%, and mortality rates with AKI of over 60% 1, 2.Ultrasound can be used to identify those at risk for AKI and assist with AKI management. Risk factors for AKI in the ICU not only include hypoperfusion but also venous congestion and volume overload. Volume overload and vascular congestion are associated with multi-organ dysfunction and worse renal outcomes. Daily and overall fluid balance, daily weights, and physical examination for edema can be inaccurate and belie true systemic venous pressure 3, 4, 5. Bedside ultrasound allows providers to evaluate vascular flow patterns and obtain a more reliable evaluation of volume status to guide and individualize therapies. Cardiac, lung, and vascular patterns on ultrasound can identify preload responsiveness, which should be assessed to safely manage ongoing fluid resuscitation and assess for signs of fluid intolerance. Here we present an overview in the use of point of care ultrasound with particular emphasis on nephro-centric strategies, namely in the identification of the type of renal injury, renal vascular flow assessment, the static measure of volume status, as well as dynamic evaluation for volume optimization in critically ill patients.

摘要

急性肾损伤(AKI)对于入住重症监护病房(ICU)的患者而言是一个重大问题,这是由于其发病率高且伴有死亡率,需要肾脏替代治疗(RRT)的AKI发生率超过5%,而AKI的死亡率超过60%[1,2]。超声可用于识别有AKI风险的患者并辅助进行AKI管理。ICU中AKI的危险因素不仅包括低灌注,还包括静脉淤血和容量超负荷。容量超负荷和血管淤血与多器官功能障碍及更差的肾脏预后相关。每日及总体液体平衡、每日体重以及水肿的体格检查可能不准确,且会掩盖真正的全身静脉压[3,4,5]。床旁超声可让医护人员评估血管血流模式,并对容量状态进行更可靠的评估,以指导并个体化治疗。超声检查的心脏、肺部和血管模式可识别前负荷反应性,应评估前负荷反应性以安全地管理正在进行的液体复苏,并评估液体不耐受的迹象。在此,我们概述了床旁超声的应用,特别强调以肾脏为中心的策略,即在识别肾损伤类型、评估肾血管血流、静态测量容量状态以及对危重症患者进行容量优化的动态评估方面的应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f5f/9994305/5b89a185dd7a/pocusj-07-15016-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f5f/9994305/9e76ba571541/pocusj-07-15016-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f5f/9994305/60d9e458f4d4/pocusj-07-15016-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f5f/9994305/5974ba3d0d99/pocusj-07-15016-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f5f/9994305/19059ffc51a6/pocusj-07-15016-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f5f/9994305/19dd4320c3e6/pocusj-07-15016-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f5f/9994305/5b89a185dd7a/pocusj-07-15016-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f5f/9994305/9e76ba571541/pocusj-07-15016-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f5f/9994305/60d9e458f4d4/pocusj-07-15016-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f5f/9994305/5974ba3d0d99/pocusj-07-15016-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f5f/9994305/19059ffc51a6/pocusj-07-15016-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f5f/9994305/19dd4320c3e6/pocusj-07-15016-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f5f/9994305/5b89a185dd7a/pocusj-07-15016-g006.jpg

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本文引用的文献

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Intravenous fluid therapy in the perioperative and critical care setting: Executive summary of the International Fluid Academy (IFA).围手术期及重症监护环境下的静脉输液治疗:国际输液学会(IFA)执行摘要
Ann Intensive Care. 2020 May 24;10(1):64. doi: 10.1186/s13613-020-00679-3.
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Feasibility of renal resistive index measurements performed by an intermediate and novice sonographer in a volunteer population.中级和新手超声检查医师对志愿者群体进行肾阻力指数测量的可行性。
Ultrasound J. 2020 May 20;12(1):28. doi: 10.1186/s13089-020-00175-6.
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Quantifying systemic congestion with Point-Of-Care ultrasound: development of the venous excess ultrasound grading system.
使用床旁超声定量评估全身充血情况:静脉淤血超声分级系统的开发
Ultrasound J. 2020 Apr 9;12(1):16. doi: 10.1186/s13089-020-00163-w.
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The Renal Resistive Index in Allografts: Is Sonographic Assessment Sufficiently Reproducible in a Routine Clinical Setting? - Reproducibility of the Renal Resistive Index.同种异体移植肾的阻力指数:在常规临床环境中超声评估的可重复性是否足够?——肾阻力指数的可重复性
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Point of care renal ultrasonography for the busy nephrologist: A pictorial review.忙碌的肾脏病学家的床旁肾脏超声检查:图文综述。
World J Nephrol. 2019 Jun 28;8(3):44-58. doi: 10.5527/wjn.v8.i3.44.
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Int J Cardiol. 2019 Apr 15;281:62-68. doi: 10.1016/j.ijcard.2019.01.055. Epub 2019 Jan 17.
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