Ruiz-Gomez D, Tarpay M M, Riley H D
Scand J Infect Dis. 1979;11(1):35-8. doi: 10.3109/inf.1979.11.issue-1.05.
The group B streptococcus has become a leading cause of neonatal infection. Despite the increasing incidence of this infection, recurrence in the same patient is extremely uncommon. This report describes three infants with proved recurrent group B streptococcal disease. All patients were treated with benzylpenicillin for at least 10 days, but, after a symptom-free interval, each developed symptoms again. Whether the illness in these patients represents a relapse or a true reinfection is difficult to determine. Various possibilities are discussed. The development of a recurrent infection indicates that presently recommended therapy may be inadequate in certain instances. Comments about epidemiology, clinical picture, antibiotic sensitivity studies, and immunity are made along with speculations about possible approaches to treatment and prevention of this infection.
B族链球菌已成为新生儿感染的主要原因。尽管这种感染的发病率在上升,但同一患者复发极为罕见。本报告描述了3例确诊为复发性B族链球菌病的婴儿。所有患者均接受苄青霉素治疗至少10天,但在无症状期后,每人再次出现症状。这些患者的疾病是复发还是真正的再感染很难确定。讨论了各种可能性。复发性感染的发生表明,目前推荐的治疗方法在某些情况下可能不足。文中对该感染的流行病学、临床表现、抗生素敏感性研究和免疫情况进行了评论,并对可能的治疗和预防方法进行了推测。