Albrektsson T, Brånemark P I, Eriksson A, Lindström J
Scand J Plast Reconstr Surg. 1978;12(3):215-23. doi: 10.3109/02844317809012997.
The preformation of bone grafts involves a two-step procedure. Primarily a mould is inserted in the donor bone. After a healing period of about 6 weeks (rabbits) the mould is removed. The performed bone graft (PBG) consists of the former cortical bone that has remodelled according to the shape of the mould. PBGs are today used clinically in selected cases of mandibular reconstruction. The present paper is the first in an animal experiment series investigating the PBG. It is shown that the PBG vascular supply is rearranged towards a more marrow-dominated circulation. Six weeks after the mould installation the bone showed evidence of accretion in the form of new-developed bone protrusions along the inner mould walls. A histochemical investigation revealed that the PBG surface cells survived the surgical trauma in a higher percentage than was the case when corresponding control grafts were examined.
骨移植预制涉及一个两步程序。首先，将一个模具插入供体骨中。经过约6周（兔子）的愈合期后，取出模具。预制骨移植物（PBG）由根据模具形状重塑的原皮质骨组成。如今，PBG在选定的下颌骨重建病例中临床使用。本文是研究PBG的动物实验系列中的第一篇。结果表明，PBG的血管供应朝着以骨髓为主的循环重新排列。安装模具六周后，骨显示出沿着模具内壁有新形成的骨突起形式的增生迹象。组织化学研究表明，PBG表面细胞在手术创伤后的存活比例高于检查相应对照移植物时的情况。
