Albrektsson T
J Bone Joint Surg Br. 1980 Aug;62(3):403-10. doi: 10.1302/0301-620X.62B3.6997321.
Tibial grafts in rabbits were studied using a microscopic technique in vivo that made it possible to photograph the "graft to be" at the donor site and then subsequently to observe the same graft repeatedly at the host site. With this method the effects on the graft tissues of varying degrees of surgical trauma have been tested. The period of follow-up ranged between 14 and 300 days. The grafts removed with minimal trauma showed a more rapid rapid of revascularisation. In this group the first vessels appeared on average seven days after grafting, whereas they took 15 days in the grafts which were more severely traumatised. Bone remodelling started when the vascular density resembled the more pattern and this occurred earlier and much more rapidly in the minimally injured grafts. It correlated with the presence of surviving cells, as shown by histochemical tests, and a causal relationship is suggested. It is concluded that control of trauma is important not only in the preparation of the host bed but also in procurement of the graft. Suggestions are given on techniques to minimise the surgical trauma.
利用一种体内显微技术对兔胫骨移植进行了研究，该技术能够在供体部位拍摄“待移植组织”，随后在宿主部位反复观察同一移植组织。通过这种方法，测试了不同程度手术创伤对移植组织的影响。随访期为14至300天。创伤最小取出的移植组织显示出更快的血管再生速度。在该组中，平均在移植后7天出现第一批血管，而在创伤更严重的移植组织中则需要15天。当血管密度类似正常模式时，骨重塑开始，这在损伤最小的移植组织中更早且更快地发生。如组织化学测试所示，这与存活细胞的存在相关，并提示存在因果关系。得出的结论是，不仅在宿主床准备中，而且在移植组织获取中，控制创伤都很重要。文中给出了关于将手术创伤降至最低的技术建议。
