Lavin M J, Marsh R J, Peart S, Rehman A
Western Ophthalmic Hospital, London.
Br J Ophthalmol. 1987 Nov;71(11):817-25. doi: 10.1136/bjo.71.11.817.
We studied 40 patients with a total of 44 retinal arterial macroaneurysms. All patients were followed up for at least six months. Macroaneurysms (MAs) have variable clinical presentations and are still frequently misdiagnosed before fluorescein angiography. Haemorrhagic MAs were most frequently misdiagnosed (75%), and had a sudden onset with a relatively poor visual outcome. Patients with these MAs had higher systolic blood pressures and significantly fewer associated retinal vein occlusions (p less than 0.05) than other types of MA. Exudative MAs caused a gradual onset of symptoms, were frequently associated with retinal vein occlusions, and were the most frequent indication for laser treatment. Only one of 10 quiescent MAs subsequently developed significant exudation or haemorrhage. We confirm the association of MAs with retinal and systemic vascular disease. In addition we found that MA patients had a significantly higher blood packed cell volume (haematocrit) than controls (p less than 0.05). Laser treatment significantly shortened the duration of MA patency (p = 0.006).
我们研究了40例患者，共44个视网膜动脉大动脉瘤。所有患者均接受了至少6个月的随访。大动脉瘤（MA）临床表现多样，在荧光素血管造影之前仍经常被误诊。出血性MA最常被误诊（75%），起病突然，视力预后相对较差。与其他类型的MA相比，这些MA患者的收缩压更高，视网膜静脉阻塞的相关病例显著更少（p<0.05）。渗出性MA症状逐渐出现，常与视网膜静脉阻塞相关，是激光治疗最常见的指征。10个静止性MA中只有1个随后出现了明显的渗出或出血。我们证实了MA与视网膜及全身血管疾病之间的关联。此外，我们发现MA患者的血液红细胞压积显著高于对照组（p<0.05）。激光治疗显著缩短了MA通畅的持续时间（p = 0.006）。
