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高龄受伤患者的最终决策,停止还是继续?终止生命支持治疗的预测因素。

The final decision among the injured elderly, to stop or to continue? Predictors of withdrawal of life supporting treatment.

机构信息

From the Division of Trauma, Critical Care, Burns, and Emergency Surgery, Department of Surgery, College of Medicine, University of Arizona, Tucson, Arizona.

出版信息

J Trauma Acute Care Surg. 2023 Jun 1;94(6):778-783. doi: 10.1097/TA.0000000000003924. Epub 2023 Mar 11.

Abstract

BACKGROUND

There is a paucity of data on factors that influence the decision regarding withdrawal of life supporting treatment (WLST) in geriatric trauma patients. We aimed to identify predictors of WLST in geriatric trauma patients.

METHODS

This retrospective analysis of the American College of Surgeons- Trauma Quality Improvement Program (2017-2019) included all severely injured (Injury Severity Score >15) geriatric trauma patients (≥65 years). Multivariable logistic regression was performed to identify independent predictors of WLST.

RESULTS

There were 155,583 patients included. Mean age was 77 ± 7 years, 55% were male, 97% sustained blunt injury, and the median Injury Severity Score was 17 [16-25]. Overall WLST rate was 10.8%. On MLR analysis, increasing age (adjusted odds ratio [aOR], 1.35; 95% confidence interval [CI], 1.33-1.37; p < 0.001), male sex (aOR, 1.14; 95% CI, 1.09-1.18; p < 0.001), White race (aOR, 1.44; 95% CI, 1.36-1.52; p < 0.001), frailty (aOR, 1.42; 95% CI, 1.34-1.50; p < 0.001), government insurance (aOR, 1.27; 95% CI, 1.20-1.33; p < 0.001), presence of advance directive limiting care (aOR, 2.55; 95% CI, 2.40-2.70; p < 0.001), severe traumatic brain injury (aOR, 1.80; 95% CI, 1.66-1.95; p < 0.001), ventilator requirement (aOR, 12.73; 95% CI, 12.09-13.39; p < 0.001), and treatment at higher level trauma centers (Level I aOR, 1.49; 95% CI, 1.42-1.57; p < 0.001; Level II aOR, 1.43; 95% CI, 1.35-1.51; p < 0.001) were independently associated with higher odds of WLST.

CONCLUSION

Our results suggest that nearly one in 10 severely injured geriatric trauma patients undergo WLST. Multiple patient and hospital related factors contribute to decision making and directed efforts are necessary to create a more standardized process.

LEVEL OF EVIDENCE

Prognostic and Epidemiological; Level III.

摘要

背景

关于影响老年创伤患者停止生命支持治疗(WLST)决策的因素的数据很少。我们旨在确定老年创伤患者 WLST 的预测因素。

方法

这是对美国外科医师学院创伤质量改进计划(2017-2019 年)的回顾性分析,包括所有严重受伤(损伤严重程度评分> 15)的老年创伤患者(≥65 岁)。采用多变量逻辑回归分析确定 WLST 的独立预测因素。

结果

共纳入 155583 例患者。平均年龄为 77 ± 7 岁,55%为男性,97%为钝性损伤,损伤严重程度评分为 17 [16-25]。总体 WLST 率为 10.8%。在 MLR 分析中,年龄增长(调整优势比[aOR],1.35;95%置信区间[CI],1.33-1.37;p < 0.001)、男性(aOR,1.14;95%CI,1.09-1.18;p < 0.001)、白人(aOR,1.44;95%CI,1.36-1.52;p < 0.001)、脆弱性(aOR,1.42;95%CI,1.34-1.50;p < 0.001)、政府保险(aOR,1.27;95%CI,1.20-1.33;p < 0.001)、存在限制护理的预立指示(aOR,2.55;95%CI,2.40-2.70;p < 0.001)、严重创伤性脑损伤(aOR,1.80;95%CI,1.66-1.95;p < 0.001)、呼吸机需求(aOR,12.73;95%CI,12.09-13.39;p < 0.001)和在较高水平创伤中心治疗(I 级 aOR,1.49;95%CI,1.42-1.57;p < 0.001;II 级 aOR,1.43;95%CI,1.35-1.51;p < 0.001)与 WLST 更高的几率独立相关。

结论

我们的结果表明,近十分之一的严重受伤老年创伤患者接受 WLST。多个患者和医院相关因素促成了决策,有必要制定更标准化的流程。

证据水平

预后和流行病学;III 级。

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