意大利BQ.1.1.37新型冠状病毒亚谱系的出现
Rise of the BQ.1.1.37 SARS-CoV-2 Sublineage, Italy.
作者信息
Focosi Daniele, Spezia Pietro Giorgio, Capria Anna-Lisa, Gueli Federico, McConnell Scott, Novazzi Federica, Pistello Mauro
机构信息
North-Western Tuscany Blood Bank, Pisa University Hospital, 56124 Pisa, Italy.
Division of Virology, Pisa University Hospital, 56124 Pisa, Italy.
出版信息
Diagnostics (Basel). 2023 Mar 6;13(5):1000. doi: 10.3390/diagnostics13051000.
BQ.1.1 has dominated the Europe and Americas COVID-19 wave across the 2022-2023 winter, and further viral evolution is expected to escape the consolidating immune responses. We report here the emergence of the BQ.1.1.37 variant in Italy, peaking in January 2022 before suffering competition by XBB.1.*. We attempted to correlate the potential fitness of BQ.1.1.37 with a unique two-amino acid insertion within the Spike protein.
BQ.1.1在2022年至2023年冬季主导了欧洲和美洲的新冠疫情浪潮，预计病毒的进一步进化将逃避正在形成的免疫反应。我们在此报告意大利出现的BQ.1.1.37变体，该变体在2022年1月达到高峰，之后受到XBB.1.*的竞争。我们试图将BQ.1.1.37的潜在适应性与刺突蛋白内独特的两个氨基酸插入相关联。
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