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奥地利女性的孕前肥胖会影响胎儿生长、分娩结局、分娩方式和流产率。

Maternal Prepregnancy Obesity Affects Foetal Growth, Birth Outcome, Mode of Delivery, and Miscarriage Rate in Austrian Women.

机构信息

Department of Evolutionary Anthropology, University of Vienna, 1030 Wien, Austria.

Clinic Donaustadt, 1220 Wien, Austria.

出版信息

Int J Environ Res Public Health. 2023 Feb 25;20(5):4139. doi: 10.3390/ijerph20054139.

Abstract

The increasing obesity rates among women of reproductive age create a major obstetrical problem as obesity during pregnancy is associated with many complications, such as a higher rate of caesarean sections. This medical record-based study investigates the effects of maternal prepregnancy obesity on newborn parameters, birth mode, and miscarriage rate. The data of 15,404 singleton births that had taken place between 2009 and 2019 at the public Danube Hospital in Vienna were enrolled in the study. Newborn parameters are birth weight, birth length, head circumference, APGAR scores, as well as pH values of the arterial and venous umbilical cord blood. In addition, maternal age, height, body weight at the beginning and the end of pregnancy, and prepregnancy body mass index (BMI) (kg/m) have been documented. The gestational week of birth, the mode of delivery, as well as the number of previous pregnancies and births, are included in the analyses. Birth length, birth weight, and head circumference of the newborn increase with increasing maternal BMI. Furthermore, with increasing maternal weight class, there tends to be a decrease in the pH value of the umbilical cord blood. Additionally, obese women have a history of more miscarriages, a higher rate of preterm birth, and a higher rate of emergency caesarean section than their normal-weight counterparts. Consequently, maternal obesity before and during pregnancy has far-reaching consequences for the mother, the child, and thus for the health care system.

摘要

生育年龄段女性肥胖率的不断上升给产科带来了重大问题,因为孕期肥胖与许多并发症有关,如剖宫产率较高。这项基于病历的研究调查了母亲孕前肥胖对新生儿参数、分娩方式和流产率的影响。该研究纳入了 2009 年至 2019 年期间在维也纳多瑙河公立医院进行的 15404 例单胎分娩的数据。新生儿参数包括出生体重、出生长度、头围、阿普加评分以及动脉和静脉脐带血的 pH 值。此外,还记录了产妇年龄、身高、妊娠开始和结束时的体重以及孕前体重指数(BMI)(kg/m)。分娩时的孕周、分娩方式以及之前的妊娠和分娩次数也包含在分析中。新生儿的出生长度、出生体重和头围随着母亲 BMI 的增加而增加。此外,随着母亲体重等级的增加,脐带血的 pH 值往往会降低。此外,肥胖女性的流产史更多、早产率更高、急诊剖宫产率也高于体重正常的女性。因此,母亲孕前和孕期的肥胖对母亲、孩子,进而对医疗保健系统都有深远的影响。

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