细胞分裂素反应因子 9 抑制花发育中的细胞分裂素反应。

Cytokinin Response Factor 9 Represses Cytokinin Responses in Flower Development.

机构信息

Institut für Angewandte Genetik, Freie Universität Berlin, Albrecht Thaer Weg 6, 14195 Berlin, Germany.

Department of Biological Sciences, Auburn University, 101 Rouse Life Sciences, Auburn, AL 36849, USA.

出版信息

Int J Mol Sci. 2023 Feb 22;24(5):4380. doi: 10.3390/ijms24054380.

DOI:10.3390/ijms24054380

PMID:36901811

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10002603/

Abstract

A multi-step phosphorelay system is the main conduit of cytokinin signal transduction. However, several groups of additional factors that also play a role in this signaling pathway have been found-among them the Cytokinin Response Factors (CRFs). In a genetic screen, CRF9 was identified as a regulator of the transcriptional cytokinin response. It is mainly expressed in flowers. Mutational analysis indicates that CRF9 plays a role in the transition from vegetative to reproductive growth and silique development. The CRF9 protein is localized in the nucleus and functions as a transcriptional repressor of (-a primary response gene for cytokinin signaling. The experimental data suggest that CRF9 functions as a repressor of cytokinin during reproductive development.

摘要

多步磷酸接力系统是细胞分裂素信号转导的主要途径。然而，已经发现了一些其他的因素也在这个信号通路中发挥作用，其中包括细胞分裂素响应因子（CRFs）。在一个遗传筛选中，CRF9 被鉴定为转录细胞分裂素反应的调节剂。它主要在花中表达。突变分析表明，CRF9 在从营养生长到生殖生长和蒴果发育的过渡中起作用。CRF9 蛋白定位于细胞核中，并作为细胞分裂素信号的 (-a 初级反应基因的转录抑制剂起作用。实验数据表明，CRF9 在生殖发育过程中作为细胞分裂素的抑制剂发挥作用。