环状 RNA 在心血管疾病中的研究进展。
The Landscape of Circular RNAs in Cardiovascular Diseases.
机构信息
Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Hubei Key Laboratory of Biological Targeted Therapy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
出版信息
Int J Mol Sci. 2023 Feb 26;24(5):4571. doi: 10.3390/ijms24054571.
Cardiovascular disease (CVD) remains the leading cause of mortality globally. Circular RNAs (circRNAs) have attracted extensive attention for their roles in the physiological and pathological processes of various cardiovascular diseases (CVDs). In this review, we briefly describe the current understanding of circRNA biogenesis and functions and summarize recent significant findings regarding the roles of circRNAs in CVDs. These results provide a new theoretical basis for diagnosing and treating CVDs.
心血管疾病（CVD）仍然是全球主要的死亡原因。环状 RNA（circRNA）因其在各种心血管疾病（CVD）的生理和病理过程中的作用而引起了广泛关注。在这篇综述中，我们简要描述了 circRNA 生物发生和功能的最新认识，并总结了 circRNA 在 CVD 中的作用的最新重要发现。这些结果为 CVD 的诊断和治疗提供了新的理论基础。
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