Subtle actions of 2-amino-4-phosphonobutyrate (APB) on the Off pathway in the mudpuppy retina.
作者信息
Arkin M S, Miller R F
机构信息
Department of Ophthalmology, Cell Biology and Physiology, Washington University School of Medicine, St. Louis, MO 63110.
出版信息
Brain Res. 1987 Nov 17;426(1):142-8. doi: 10.1016/0006-8993(87)90433-1.
PMID:3690311
Abstract
The principal action of 2-amino-4-phosphonobutyrate (APB) applied to the retina is the elimination of the On-bipolar cell light response. In this study, we report that APB also has more subtle effects; it sometimes enhances Off responses of Off bipolar cells and On, Off, and On-Off inner retina neurons. Possible mechanisms for this enhancement are considered.
摘要
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