GC-MS 分析欧防风（伞形科）根的精油及其杀线虫活性。
GC-MS Analysis of the Essential Oil from H. Wolff (Apiaceae) Roots and Their Nematicidal Activity.
机构信息
School of Chemistry, Biology and Environment, Yuxi Normal University, Yuxi 653100, China.
Faculty Affairs Center, Yuxi Normal University, Yuxi 653100, China.
出版信息
Molecules. 2023 Feb 27;28(5):2205. doi: 10.3390/molecules28052205.
The essential oil (EO) was extracted from aerial parts with insecticidal and fungicidal activity. Herein, the hydro-distilled essential oils of H. Wolff roots were determined by GC-MS. A total of 37 components were identified, ()-beta-caryophyllene (10.49%), -geranylgeranyl (6.64%), ()-2-decenal (6.17%) and germacrene-D (4.28%). The essential oil of H. Wolff had nematicidal toxicity against with a LC value of 53.45 μg/mL. The subsequent bioassay-guided investigation led to the isolation of three active constituents: falcarinol, ()-2-decenal, and octanoic acid. The falcarinol demonstrated the strongest toxicity against (LC = 8.52 μg/mL). The octanoic acid and ()-2-decenal also exhibited moderate toxicity against (LC = 65.56 and 176.34 μg/mL, respectively). The LC of falcarinol for the toxicity of was 7.7 and 21 times than that of octanoic acid and ()-2-decenal, respectively. Our findings demonstrate that the essential oil from H. Wolff roots and their isolates may be developed as a promising natural nematicide.
从具有杀虫和杀菌活性的地上部分提取了精油。在此，通过 GC-MS 确定了 H. Wolff 根的水蒸馏精油。共鉴定出 37 种成分，其中（）-β-石竹烯（10.49％），-香叶基倍半萜烯（6.64％），（）-2-癸烯醛（6.17％）和大根香叶烯-D（4.28％）。H. Wolff 的精油对 具有杀线虫毒性，LC 值为 53.45μg/mL。随后的基于生物测定的研究导致分离出三种活性成分：法卡林醇，（）-2-癸烯醛和辛酸。法卡林醇对 （LC = 8.52μg/mL）表现出最强的毒性。辛酸和（）-2-癸烯醛对 （LC = 65.56 和 176.34μg/mL）也表现出中等毒性。法卡林醇对 毒性的 LC 值分别是辛酸和（）-2-癸烯醛的 7.7 和 21 倍。我们的研究结果表明，H. Wolff 根的精油及其分离物可能被开发为有前途的天然杀线虫剂。
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