Department of Chemistry, North Caucasus Federal University, 1a Pushkin St., 355009 Stavropol, Russia.
Molecules. 2023 Mar 2;28(5):2324. doi: 10.3390/molecules28052324.
A straightforward three-step procedure affording a wide range of novel 7-aryl substituted paullone derivatives was developed. This scaffold is structurally similar to 2-(1-indol-3-yl)acetamides-promising antitumor agents-hence, could be useful for the development of a new class of anticancer drugs.
开发了一种直截了当的三步法,可获得广泛的新型 7-芳基取代的 paullone 衍生物。该支架结构与 2-(1-吲哚-3-基)乙酰胺类似,是有前途的抗肿瘤剂-因此,可用于开发一类新的抗癌药物。