Shafran B, Roke M E, Barr R M, Cairncross J G
Department of Clinical Neurological Sciences, University of Western Ontario, London, Canada.
Can J Neurol Sci. 1987 Nov;14(4):600-2.
A 60 year old man with chronic lymphocytic leukemia (CLL) developed a subacute neurological illness associated with multiple contrast enhancing lesions on CT scan. At autopsy large demyelinating lesions characteristic of progressive multifocal leukoencephalopathy (PML) were found in the right cerebral hemisphere surrounded by a dense leukemic infiltrate. The areas of contrast enhancement, highly unusual for PML, coincided with the CLL infiltrate.