Vairo Francesco, Leone Sara, Mazzotta Valentina, Piselli Pierluca, De Carli Gabriella, Lanini Simone, Maggi Fabrizio, Nicastri Emanuele, Gagliardini Roberta, Vita Serena, Siddu Andrea, Rezza Giovanni, Barca Alessandra, Vaia Francesco, Antinori Andrea, Girardi Enrico
National Institute for Infectious Diseases 'Lazzaro Spallanzani' (IRCCS), Rome, Italy.
National Institute for Infectious Diseases 'Lazzaro Spallanzani' (IRCCS), Rome, Italy.
Int J Infect Dis. 2023 May;130:83-85. doi: 10.1016/j.ijid.2023.03.005. Epub 2023 Mar 9.
A pre-exposure vaccination campaign to prevent the spread of the mpox virus was initiated in Italy in August 2022. We explore the possible factors affecting the trend of mpox cases in an Italian region (Lazio) with a rapid roll-out of the vaccination campaign.
We estimated the impact of the communication and vaccination campaign by fitting a Poisson segmented regression model. Results By September 30, 2692, high-risk men who have sex with men had received at least one dose of vaccine, with a vaccination coverage of 37%. The analysis of surveillance data showed a significant decreasing trend in the number of mpox cases starting from the second week after vaccination (incidence rate ratio 0.452 [0.331-0.618]).
The reported trend in mpox cases is likely to result from a combination of multiple social and public health factors combined with a vaccination campaign.
2022年8月，意大利启动了一项暴露前疫苗接种运动，以防止猴痘病毒传播。我们探讨了在一个迅速开展疫苗接种运动的意大利地区（拉齐奥），影响猴痘病例趋势的可能因素。
我们通过拟合泊松分段回归模型来估计宣传和疫苗接种运动的影响。
截至2022年9月30日，2692名与男性发生性行为的高危男性至少接种了一剂疫苗，疫苗接种覆盖率为37%。监测数据分析显示，从接种疫苗后的第二周开始，猴痘病例数呈显著下降趋势（发病率比为0.452[0.331-0.618]）。
报告的猴痘病例趋势可能是多种社会和公共卫生因素与疫苗接种运动共同作用的结果。
