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神经外科高频超声消融术。

High-Frequency Ultrasound Ablation in Neurosurgery.

机构信息

Department of Neurosurgery, University of Virginia, School of Medicine, PO Box 800212, Charlottesville, VA 22908, USA.

Department of Neurosurgery, University of Virginia, School of Medicine, PO Box 800212, Charlottesville, VA 22908, USA.

出版信息

Neurosurg Clin N Am. 2023 Apr;34(2):301-310. doi: 10.1016/j.nec.2022.12.001. Epub 2023 Jan 31.

Abstract

Modern transcranial magnetic resonance-guided focused ultrasound is an incisionless, ablative treatment modality for a growing number of neurologic disorders. This procedure selectively destroys a targeted volume of cerebral tissue and relies on real-time MR thermography to monitor tissue temperatures. By focusing on a submillimeter target through a hemispheric phased array of transducers, ultrasound waves pass through the skull and avoid overheating and brain damage. High-intensity focused ultrasound techniques are increasingly used to create safe and effective stereotactic ablations for medication-refractory movement and other neurologic and psychiatric disorders.

摘要

现代经颅磁共振引导聚焦超声是一种针对越来越多的神经疾病的非侵入性、消融性治疗方法。该方法选择性地破坏靶向脑区的组织,依赖实时磁共振热成像来监测组织温度。通过在半球形相控阵换能器上聚焦亚毫米级的靶点,超声波可以穿透颅骨,避免过热和脑损伤。高强度聚焦超声技术越来越多地用于创建安全有效的立体定向消融,以治疗药物难治性运动障碍和其他神经和精神疾病。

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