Fleeman Linda, Gilor Chen
Animal Diabetes Australia, 5 Hood Street, Collingwood, Victoria 3066, Australia.
Small Animal Internal Medicine, Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, 2015 Southwest 16th Avenue, Gainesville, FL 32608, USA.
Vet Clin North Am Small Anim Pract. 2023 May;53(3):635-644. doi: 10.1016/j.cvsm.2023.02.004. Epub 2023 Mar 9.
No insulin formulation should be considered best by default for management of feline diabetes. Rather, the choice of insulin formulation should be tailored to the specific clinical situation. In most cats that have some residual beta cell function, administering only a basal insulin might lead to complete normalization of blood glucose concentrations. Basal insulin requirements are constant throughout the day. Therefore, for an insulin formulation to be effective and safe as a basal insulin, its action should be roughly the same every hour of the day. At present, only insulin glargine U300 approaches this definition in cats.
在猫糖尿病的管理中，不应默认某种胰岛素制剂是最佳的。相反，胰岛素制剂的选择应根据具体临床情况进行调整。在大多数仍有一些残余β细胞功能的猫中，仅给予基础胰岛素可能会使血糖浓度完全恢复正常。基础胰岛素的需求量在一天中是恒定的。因此，一种胰岛素制剂要作为基础胰岛素有效且安全，其作用在一天中的每一小时都应大致相同。目前，在猫中只有甘精胰岛素U300接近这一定义。
