Department of Health, Medicine and Caring Sciences, Unit of Physiotherapy, Linköping University, Linköping, Sweden.
Center for Medical Image Science and Visualization (CMIV), Linköping University, Linköping, Sweden.
BMC Musculoskelet Disord. 2023 Mar 11;24(1):181. doi: 10.1186/s12891-023-06289-x.
The underlying pathophysiological mechanisms of chronic Whiplash Associated Disorders (WAD) are not fully understood. More knowledge of morphology is needed to better understand the disorder, improve diagnostics and treatments. The aim was to investigate dorsal neck muscle volume (MV) and muscle fat infiltration (MFI) in relation to self-reported neck disability among 30 participants with chronic WAD grade II-III compared to 30 matched healthy controls.
MV and MFI at spinal segments C4 through C7 in both sexes with mild- to moderate chronic WAD (n = 20), severe chronic WAD (n = 10), and age- and sex matched healthy controls (n = 30) was compared. Muscles: trapezius, splenius, semispinalis capitis and semispinalis cervicis were segmented by a blinded assessor and analyzed.
Higher MFI was found in right trapezius (p = 0.007, Cohen's d = 0.9) among participants with severe chronic WAD compared to healthy controls. No other significant difference was found for MFI (p = 0.22-0.95) or MV (p = 0.20-0.76).
There are quantifiable changes in muscle composition of right trapezius on the side of dominant pain and/or symptoms, among participants with severe chronic WAD. No other statistically significant differences were shown for MFI or MV. These findings add knowledge of the association between MFI, muscle size and self-reported neck disability in chronic WAD.
NA. This is a cross-sectional case-control embedded in a cohort study.
慢性挥鞭样损伤相关障碍（WAD）的潜在病理生理机制尚未完全阐明。为了更好地理解该疾病、提高诊断和治疗效果，需要更多关于形态学的知识。本研究旨在探讨 30 名慢性 WAD II-III 级患者与 30 名匹配健康对照者的颈后肌肉体积（MV）和肌肉脂肪浸润（MFI）与自我报告的颈部残疾之间的关系。
比较了男女轻度至中度慢性 WAD（n = 20）、重度慢性 WAD（n = 10）患者及年龄和性别匹配的健康对照组（n = 30）的 C4 至 C7 脊柱节段的 MV 和 MFI。使用盲法评估员对斜方肌、头半棘肌、头夹肌和颈半棘肌进行了分段和分析。
与健康对照组相比，重度慢性 WAD 患者右侧斜方肌的 MFI 更高（p = 0.007，Cohen's d = 0.9）。MFI（p = 0.22-0.95）或 MV（p = 0.20-0.76）均无其他显著差异。
在重度慢性 WAD 患者中，与优势疼痛和/或症状侧的斜方肌相比，存在肌肉组成的可量化变化。MFI 或 MV 没有显示出其他统计学上的显著差异。这些发现增加了慢性 WAD 中 MFI、肌肉大小和自我报告颈部残疾之间的关联知识。
无。这是一项在队列研究中嵌入的横断面病例对照研究。
