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颈部特异性运动结合和不结合基于互联网的支持对慢性颈源性眩晕/不稳的疗效:一项随机对照试验的二次分析。

Effectiveness of neck-specific exercises with and without internet-based support on dizziness/unsteadiness in chronic whiplash-associated disorders: Secondary analyses of a randomised controlled trial.

机构信息

Department of Health, Medicine and Caring Sciences, Unit of Physiotherapy, Linköping University, Linköping, Sweden.

Occupational and Environmental Medicine Centre, Department of Health, Medicine and Caring Sciences, Unit of Clinical Medicine, Linköping University, Linköping, Sweden.

出版信息

PLoS One. 2024 Oct 7;19(10):e0311145. doi: 10.1371/journal.pone.0311145. eCollection 2024.

Abstract

AIM

To investigate the effectiveness in individuals with chronic whiplash-associated disorders (WADs) of neck-specific exercise (NSE) supervised by a physiotherapist twice a week for 12 weeks versus neck-specific exercise with internet support and four physiotherapy visits (NSEIT) regarding dizziness, unsteadiness and balance, and to investigate the differences between WAD grades.

METHOD

This is a secondary analysis of a prospective randomised multicentre study (RCT) with concealed allocation (ClinicalTrials.gov Protocol ID: NCT03022812). The outcomes were dizziness measured on the Dizziness Handicap Inventory (DHI); dizziness at rest and during activity and unsteadiness using visual analogue scales; and standing on one leg with eyes closed (SOLEC). Participants (n = 140) were randomised to NSE or NSEIT. Measurements were obtained at baseline, and at three- and 15-month follow-ups by assessor-blinded investigators.

RESULTS

There were no significant differences between NSEIT and NSE in any of the outcomes (p>0.38). Both NSEIT and NSE improved over time (p<0.02; effect size (ES) = 0.74-1.01) in DHI score and dizziness during activity. There was a significant group-by-time interaction effect in dizziness (at rest: p = 0.035; ES: 0.66; and during activity: p = 0.016; ES: 1.24) between WAD grades. Individuals with WAD grade 3 had dizziness/unsteadiness to a greater extent and improved in all outcomes over time (p<0.04) compared to those with WAD grade 2, except for SOLEC.

CONCLUSIONS

There were no significant group differences between NSEIT and NSE. Both groups decreased in terms of self-reported dizziness (DHI, dizziness during activity), with medium to large effect size. Those with WAD grade 3 have dizziness/unsteadiness to a greater extent than those with WAD grade 2. Despite improvements, many participants still reported dizziness at 15-month follow-up, and additional balance training and/or vestibular exercise may be investigated for potential additional effect.

摘要

目的

探讨每周由物理治疗师监督两次、为期 12 周的颈部特定运动(NSE)与具有互联网支持和四次物理治疗就诊的颈部特定运动(NSEIT)对慢性颈源性眩晕相关障碍(WAD)患者的有效性,以评估其对头晕、不稳定和平衡的影响,并研究 WAD 分级之间的差异。

方法

这是一项前瞻性随机多中心研究(RCT)的二次分析(ClinicalTrials.gov 方案 ID:NCT03022812),采用隐匿分组。结局指标为眩晕障碍量表(DHI)评估的头晕;静息和活动时的头晕及不稳定性采用视觉模拟量表评估;闭眼单腿站立(SOLEC)评估。共有 140 名参与者被随机分配至 NSE 或 NSEIT 组。评估者盲法评估了参与者在基线、3 个月和 15 个月时的结果。

结果

在任何结局指标上,NSEIT 与 NSE 之间均无显著差异(p>0.38)。NSEIT 和 NSE 组的 DHI 评分和活动时的头晕均随时间改善(p<0.02;效应量(ES)=0.74-1.01)。WAD 分级之间的组间交互效应在头晕(静息时:p=0.035;ES:0.66;活动时:p=0.016;ES:1.24)方面有显著差异。WAD 3 级患者头晕/不稳定性更为严重,且所有结局指标随时间改善(p<0.04),但 SOLEC 除外,与 WAD 2 级患者相比。

结论

NSEIT 与 NSE 之间无显著组间差异。两组患者的自我报告头晕(DHI、活动时的头晕)均有所改善,效应量为中到大。WAD 3 级患者的头晕/不稳定性比 WAD 2 级患者更为严重。尽管有所改善,但仍有许多参与者在 15 个月随访时仍报告头晕,可能需要进一步进行平衡训练和/或前庭锻炼,以寻求潜在的额外疗效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/727f/11457992/b925f1a49a74/pone.0311145.g001.jpg

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