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比较 COVID-19 大流行前后儿科急诊就诊的自杀未遂、自残和自杀意念:系统评价和荟萃分析。

Comparison of paediatric emergency department visits for attempted suicide, self-harm, and suicidal ideation before and during the COVID-19 pandemic: a systematic review and meta-analysis.

机构信息

Department of Psychology, University of Calgary, Calgary, AB, Canada; Alberta Children's Hospital Research Institute, Calgary, AB, Canada.

Department of Psychiatry, Hospital for Sick Children, Toronto, ON, Canada; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.

出版信息

Lancet Psychiatry. 2023 May;10(5):342-351. doi: 10.1016/S2215-0366(23)00036-6. Epub 2023 Mar 9.

Abstract

BACKGROUND

There is a lack of consensus about the effect of the COVID-19 pandemic on the mental health of children and adolescents. We aimed to compare rates of paediatric emergency department visits for attempted suicide, self-harm, and suicidal ideation during the pandemic with those before the pandemic.

METHODS

For this systematic review and meta-analysis, we searched MEDLINE, Embase, and PsycINFO for studies published between Jan 1, 2020, and Dec 19, 2022. Studies published in English with data on paediatric (ie, those aged <19 years) emergency department visits before and during the COVID-19 pandemic were included. Case studies and qualitative analyses were excluded. Changes in attempted suicide, self-harm, suicidal ideation, and other mental-illness indicators (eg, anxiety, depression, and psychosis) were expressed as ratios of the rates of emergency department visits during the pandemic compared with those before the pandemic, and we analysed these with a random-effects meta-analysis. This study was registered with PROSPERO, CRD42022341897.

FINDINGS

10 360 non-duplicate records were retrieved, which yielded 42 relevant studies (with 130 sample-estimates) representing 11·1 million emergency department visits for all indications of children and adolescents across 18 countries. The mean age of the samples of children and adolescents across studies was 11·7 years (SD 3·1, range 5·5-16·3), and there were on average 57·6% girls and 43·4% boys as a proportion of emergency department visits for any health reasons (ie, physical and mental). Only one study had data related to race or ethnicity. There was good evidence of an increase in emergency department visits for attempted suicide during the pandemic (rate ratio 1·22, 90% CI 1·08-1·37), modest evidence of an increase in emergency department visits for suicidal ideation (1·08, 0·93-1·25), and good evidence for only a slight change in self-harm (0·96, 0·89-1·04). Rates of emergency department visits for other mental-illness indications showed very good evidence of a decline (0·81, 0·74-0·89), and paediatric visits for all health indications showed strong evidence of a reduction (0·68, 0·62-0·75). When rates for attempted suicide and suicidal ideation were combined as a single measure, there was good evidence of an increase in emergency department visits among girls (1·39, 1·04-1·88) and only modest evidence of an increase among boys (1·06, 0·92-1·24). Self-harm among older children (mean age 16·3 years, range 13·0-16·3) showed good evidence of an increase (1·18, 1·00-1·39), but among younger children (mean age 9·0 years, range 5·5-12·0) there was modest evidence of a decrease (0·85, 0·70-1·05).

INTERPRETATION

The integration of mental health support within community health and the education system-including promotion, prevention, early intervention, and treatment-is urgently needed to increase the reach of mental health support that can mitigate child and adolescent mental distress. In future pandemics, increased resourcing in some emergency department settings would help to address their expected increase in visits for acute mental distress among children and adolescents.

FUNDING

None.

摘要

背景

关于 COVID-19 大流行对儿童和青少年心理健康的影响,目前尚未达成共识。本研究旨在比较大流行期间和大流行前,儿科急诊就诊的自杀未遂、自伤和自杀意念的发生率。

方法

本系统评价和荟萃分析检索了 2020 年 1 月 1 日至 2022 年 12 月 19 日期间发表的 MEDLINE、Embase 和 PsycINFO 中的研究。纳入了发表在英语期刊上、有大流行前后儿童(即年龄<19 岁)急诊就诊数据的研究。排除病例研究和定性分析。自杀未遂、自伤、自杀意念和其他精神疾病指标(如焦虑、抑郁和精神病)的变化表示为大流行期间与大流行前相比急诊就诊率的比值,我们使用随机效应荟萃分析对此进行分析。本研究在 PROSPERO 上注册,CRD42022341897。

结果

共检索到 10360 份非重复记录,其中 42 项相关研究(130 个样本估计值)代表了 18 个国家的所有儿童和青少年的指示下 1110 万例儿科急诊就诊。研究样本中儿童和青少年的平均年龄为 11.7 岁(SD 3.1,范围 5.5-16.3),因任何健康原因(即身体和精神)就诊的儿童和青少年中,女孩平均占 57.6%,男孩占 43.4%。只有一项研究有与种族或民族相关的数据。有充分证据表明自杀未遂急诊就诊率在大流行期间有所增加(率比 1.22,90%CI 1.08-1.37),有中等证据表明自杀意念急诊就诊率有所增加(1.08,0.93-1.25),仅有轻微变化的自伤急诊就诊率的证据很好(0.96,0.89-1.04)。其他精神疾病指标的急诊就诊率显示出非常好的下降证据(0.81,0.74-0.89),所有健康指标的儿科就诊率显示出强有力的下降证据(0.68,0.62-0.75)。当自杀未遂和自杀意念的比率结合作为单一指标时,女孩急诊就诊率有充分证据表明有所增加(1.39,1.04-1.88),而男孩仅有中等证据表明有所增加(1.06,0.92-1.24)。年龄较大的儿童(平均年龄 16.3 岁,范围 13.0-16.3)的自伤率有充分证据表明有所增加(1.18,1.00-1.39),但年龄较小的儿童(平均年龄 9.0 岁,范围 5.5-12.0)的自伤率有中等证据表明有所减少(0.85,0.70-1.05)。

解释

需要将心理健康支持纳入社区卫生和教育系统,包括促进、预防、早期干预和治疗,以增加心理健康支持的覆盖面,从而减轻儿童和青少年的精神困扰。在未来的大流行中,增加一些急诊部门的资源将有助于解决预计儿童和青少年急性精神困扰就诊率的增加。

结论

在大流行期间,儿科急诊就诊的自杀未遂、自伤和自杀意念的发生率有所增加,而其他精神疾病指标的急诊就诊率则有所下降。需要将心理健康支持纳入社区卫生和教育系统,以增加心理健康支持的覆盖面,从而减轻儿童和青少年的精神困扰。

局限性

仅纳入了英文文献,可能存在发表偏倚。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c261/10097509/05f0eac2a713/gr1_lrg.jpg

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