The School of Medicine, The University of Jordan, Amman, Jordan.
King Hussein Cancer Center, Amman, Jordan.
Hum Fertil (Camb). 2023 Feb;26(1):146-152. doi: 10.1080/14647273.2023.2181106. Epub 2023 Mar 13.
Due to the paucity of literature on COVID-19 and menstrual irregularities, this study aims to investigate the effect of COVID-19 infection on menstrual changes in premenopausal women within the Middle East and North Africa (MENA) region. A cross-sectional investigation utilizing a self-administered online questionnaire was conducted between July and August of 2021. A total of 499 females participated in our survey with a mean age of 35.2 ± 8.4 years. The majority of participants had regular periods (74.1%) and were disease free (81.6%). Mild, moderate, and severe symptoms were documented in 58.9%, 26.7%, and 3.0% of the studied cohort, respectively. Females experienced significantly more menstrual abnormalities after COVID-19 infection than during the pandemic prior to infection ( < 0.001). Those females were significantly older ( = 0.031), had more severe symptoms ( = 0.029), and were more likely to have experienced irregularities during the epidemic ( < 0.001). COVID-19 infection seems to induce menstrual abnormalities in premenopausal females. These abnormalities could manifest as increased frequency or severity and are associated with older women.
由于 COVID-19 和月经不规律相关文献较少，本研究旨在调查中东和北非（MENA）地区围绝经期前女性 COVID-19 感染对月经变化的影响。2021 年 7 月至 8 月期间采用横断面调查，使用自我管理的在线问卷进行。共有 499 名女性参与了我们的调查，平均年龄为 35.2±8.4 岁。大多数参与者的月经规律（74.1%），无疾病（81.6%）。研究队列中分别有 58.9%、26.7%和 3.0%的患者记录到轻度、中度和重度症状。与感染 COVID-19 之前相比，感染 COVID-19 后女性的月经异常明显更多（<0.001）。这些女性的年龄明显更大（=0.031），症状更严重（=0.029），并且在疫情期间更有可能出现不规则（<0.001）。COVID-19 感染似乎会导致围绝经期前女性出现月经异常。这些异常可能表现为频率或严重程度增加，并且与年龄较大的女性有关。
