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加拿大大麻合法化对安大略省和阿尔伯塔省青年因大麻相关障碍和中毒前往急诊部的影响,2015-2019 年。

Impact of Canada's cannabis legalisation on youth emergency department visits for cannabis-related disorders and poisoning in Ontario and Alberta, 2015-2019.

机构信息

University of Northern British Columbia, Northern Medical Program, Prince George, Canada.

Centre for Addiction and Mental Health, Human Brain Laboratory, Toronto, Canada.

出版信息

Drug Alcohol Rev. 2023 Jul;42(5):1104-1113. doi: 10.1111/dar.13637. Epub 2023 Mar 13.

Abstract

INTRODUCTION

Although there is momentum towards legalising adult recreational cannabis use worldwide, the extent of youth cannabis-related harm associated with legalisation is still uncertain. The current study aimed to assess whether the initial implementation of Canada's cannabis legalisation (via the Cannabis Act) on 17 October 2018 might be associated with youth harm, as assessed by emergency department visits for cannabis-related disorders/poisoning.

METHODS

We used Ontario and Alberta, Canada emergency department data from 1 April 2015 to 31 December 2019. We identified all cannabis-related disorders/poisoning (ICD-10 CA: F12.X, T40.7) emergency department visits of youth (n = 13,615), defined as patients younger than the minimum legal cannabis sales age (18 years, Alberta; 19 years, Ontario). Seasonal Autoregressive Integrated Moving Average (SARIMA) models were employed to assess the impact of legalisation on weekly counts of cannabis-related harms.

RESULTS

The final SARIMA intervention (step) parameter indicated a post-legalisation increase of 14.7 (95% confidence interval [CI] 5.0; 24.3, p < 0.01) weekly youth cannabis-related disorder/poisoning presentations to Ontario/Alberta emergency department settings, equivalent to an increase of 20.0% (95% CI 6.2%; 33.9%). There was no evidence of associations between cannabis legalisation and comparison series of youth alcohol, opioid or appendicitis emergency department episodes.

DISCUSSION/CONCLUSION: Our findings require replication and extension but are consistent with the possibility that the implementation of the Cannabis Act was associated with an increase in youth cannabis-related presentations to Ontario/Alberta emergency departments.

摘要

引言

尽管全球范围内有推动成人娱乐用大麻合法化的势头,但大麻合法化与青少年相关危害的程度仍不确定。本研究旨在评估加拿大于 2018 年 10 月 17 日实施的大麻合法化(通过《大麻法案》)是否可能与青少年伤害有关,评估方法是通过因大麻相关障碍/中毒而前往急诊的人数。

方法

我们使用了加拿大安大略省和艾伯塔省的急诊部门数据,时间范围为 2015 年 4 月 1 日至 2019 年 12 月 31 日。我们确定了所有与大麻相关的障碍/中毒(ICD-10 CA:F12.X,T40.7)的青少年(n=13615)急诊病例,定义为年龄小于最低合法销售大麻年龄(安大略省 18 岁,艾伯塔省 19 岁)的患者。季节性自回归综合移动平均(SARIMA)模型用于评估合法化对每周大麻相关危害计数的影响。

结果

最终的 SARIMA 干预(步骤)参数表明,在安大略/艾伯塔省急诊部门中,大麻相关障碍/中毒青少年就诊人数每周增加 14.7(95%置信区间 [CI] 5.0;24.3,p<0.01),相当于增加 20.0%(95% CI 6.2%;33.9%)。没有证据表明大麻合法化与青少年酒精、阿片类药物或阑尾炎急诊发作的比较系列之间存在关联。

讨论/结论:我们的研究结果需要进一步复制和扩展,但与大麻法案的实施可能与安大略/艾伯塔省急诊部门青少年大麻相关就诊人数增加有关的可能性一致。

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