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现代移植实践中的转化研究与创新:来自希腊及世界各地的范例

Translational research and innovation in modern transplant practice: Paradigms from Greece and around the world.

作者信息

Tsoulfas Georgios, Boletis Ioannis, Papalois Vassilios

机构信息

Department of Transplantation Surgery, Aristotle University School of Medicine, Thessaloniki 54124, Greece.

Department of Nephrology, EKPA University, Athens 11527, Greece.

出版信息

World J Transplant. 2023 Feb 18;13(2):25-27. doi: 10.5500/wjt.v13.i2.25.

Abstract

The continuous clinical and technological advances, together with the social, health and economic challenges that the global population faces, have created an environment where the evolution of the field of transplantation is essentially necessary. The goal of this special issue is to provide a picture of the current status of transplantation in Greece as well as in many other countries in Europe and around the world. Authors from Greece and several other countries provide us with valuable insight into their respective areas of transplant expertise, with a main focus on the field of translational research and innovation. The papers that are part of this Special Issue "Translational Research and Innovation and the current status of Transplantation in Greece" have presented innovative and meaningful approaches in modern transplant research and practice. They provide us with a clear overview of the current landscape in transplantation, including liver transplantation in the context of a major pandemic, the evolution of living donor kidney transplantation or the evolution of the effect of hepatitis C virus infection in transplantation, while at the same time explore more recent challen ges, such as the issue of frailty in the transplant candidate and the changes brought by newer treatments, such as immunotherapy, in transplant oncology. Additionally, they offer us a glimpse of the effect that technological innovations, such as virtual reality, can have on transplantation, both in terms of clinical and educational aspects. Just as critical is the fact that this Special Issue emphasizes the multidisciplinary, collaborative efforts currently taking place that link transplant research and innovation with other cutting-edge disciplines such as bioengineering, advanced information technology and artificial intelligence. In this Special Issue, in addition to the clinical and research evolution of the field of transplantation, we are witnessing the importance of interdisciplinary collaboration in medicine.

摘要

持续的临床和技术进步,以及全球人口面临的社会、健康和经济挑战,营造了一个移植领域发展必不可少的环境。本期特刊的目标是呈现希腊以及欧洲和世界其他许多国家移植领域的现状。来自希腊和其他几个国家的作者为我们提供了有关其各自移植专业领域的宝贵见解,主要聚焦于转化研究与创新领域。作为本期特刊“转化研究与创新以及希腊移植领域现状”一部分的论文,展示了现代移植研究与实践中创新且有意义的方法。它们为我们清晰概述了移植领域的当前状况,包括在重大疫情背景下的肝移植、活体供肾移植的发展,或丙型肝炎病毒感染在移植中的影响演变,同时还探讨了更新的挑战,比如移植候选者的衰弱问题以及免疫疗法等新治疗方法给移植肿瘤学带来的变化。此外,它们还让我们得以一窥虚拟现实等技术创新在临床和教育方面对移植可能产生的影响。同样关键的是,本期特刊强调了当前正在进行的多学科协作努力,这些努力将移植研究与创新同生物工程、先进信息技术和人工智能等其他前沿学科联系起来。在本期特刊中,除了移植领域临床和研究的发展,我们还见证了医学中跨学科协作的重要性。

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本文引用的文献

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Changing landscape in living kidney donation in Greece.希腊活体肾捐献情况的变化态势
World J Transplant. 2023 Feb 18;13(2):28-35. doi: 10.5500/wjt.v13.i2.28.
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Surgical chest complications after liver transplantation.肝移植术后的胸部手术并发症
World J Transplant. 2022 Nov 18;12(11):359-364. doi: 10.5500/wjt.v12.i11.359.

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