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希腊活体肾捐献情况的变化态势

Changing landscape in living kidney donation in Greece.

作者信息

Karydis Nikolaos, Maroulis Ioannis

机构信息

Department of General Surgery and Transplantation, University of Patras, Patras 26504, Greece.

Department of General Surgery, University of Patras, Patras 26504, Greece.

出版信息

World J Transplant. 2023 Feb 18;13(2):28-35. doi: 10.5500/wjt.v13.i2.28.

Abstract

Patients with end-stage renal disease in Greece are facing long waiting times to receive a kidney transplant from a deceased donor. Living kidney donation offers a valuable alternative that provides optimal outcomes and significantly expands the donor pool but still remains relatively underutilised. Developments around the world in the field of kidney transplantation mandate a change in current practice to include additional options for living donation through paired exchange, antibody-incompatible transplantation and other strategies, following careful consideration of the cultural and ethical factors involved in these complex clinical decisions. An increase in living donation rates may be achieved in several ways, including targeted campaigning to overcome potential barriers. Educating clinicians on transplantation will prove as equally important as informing patients and prospective donors but requires training and resources. Adoption of established practices and implementation of new strategies must be tailored to the needs of the Greek donor and recipient population. Local beliefs about donation, perception of associated risk and other social characteristics must be considered in the design of future strategies. Facilitating living donation in a safe environment with appropriate donor and recipient education will form the solid foundation of a new era of kidney transplantation in Greece.

摘要

希腊终末期肾病患者等待已故捐赠者肾脏移植的时间很长。活体肾捐赠提供了一个有价值的替代方案,能带来最佳结果并显著扩大捐赠者群体,但仍未得到充分利用。全球肾脏移植领域的发展要求改变当前做法,在仔细考虑这些复杂临床决策中涉及的文化和伦理因素后,纳入通过配对交换、抗体不相容移植及其他策略进行活体捐赠的更多选择。提高活体捐赠率可通过多种方式实现,包括开展有针对性的宣传活动以克服潜在障碍。事实证明,对临床医生进行移植方面的教育与告知患者及潜在捐赠者同样重要,但这需要培训和资源。采用既定做法和实施新策略必须根据希腊捐赠者和受赠者群体的需求进行调整。在设计未来策略时,必须考虑当地关于捐赠的观念、对相关风险的认知及其他社会特征。在安全环境中促进活体捐赠并对捐赠者和受赠者进行适当教育,将为希腊肾脏移植新时代奠定坚实基础。

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