Gooseman Michael R, Brunelli Alessandro, Chaudhuri Nilanjan, Milton Richard, Tcherveniakov Peter, Papagiannopoulos Kostas, Valuckiene Laura
Department of Cardiothoracic Surgery, Castle Hill Hospital, Hull University Teaching Hospitals, Cottingham, UK.
Department of Thoracic Surgery, St. James's University Hospital, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
J Thorac Dis. 2023 Feb 28;15(2):858-865. doi: 10.21037/jtd-22-623. Epub 2022 Oct 17.
We designed this study to investigate the rate and risk factors of prolonged air leak (PAL) in patients undergoing pulmonary segmentectomy in our unit.
We performed a retrospective cohort study on 191 patients undergoing pulmonary segmentectomy (January 2017-August 2021). A PAL was defined as an air leak >5 days.
One hundred and sixty-eight segmentectomies were performed using video-assisted thoracoscopic surgery (VATS), 13 were open operations and 10 were robotic. PAL occurred in 36 patients (19%). Their average post-operative stay was 2.4 days longer than those without PAL. Logistic regression analysis showed that a low preoperative carbon monoxide lung diffusion capacity (DLCO) (OR 0.98, P<0.001), low body mass index (BMI) (OR 0.95, P=0.002) and the performance of complex segmentectomies (OR 2.2, P<0.001). were significantly associated with PAL.
Pulmonary segmentectomies are associated with a not negligible risk of PAL when using real world data, especially in patients with compromised pulmonary function and after complex segmentectomies. This finding is useful to inform the decision-making process.
我们开展这项研究旨在调查在本单位接受肺段切除术的患者中持续性漏气(PAL)的发生率及危险因素。
我们对191例接受肺段切除术的患者(2017年1月至2021年8月)进行了一项回顾性队列研究。PAL定义为漏气超过5天。
168例肺段切除术采用电视辅助胸腔镜手术(VATS),13例为开放手术,10例为机器人手术。36例患者(19%)发生了PAL。他们的术后平均住院时间比未发生PAL的患者长2.4天。逻辑回归分析显示,术前一氧化碳肺弥散量(DLCO)低(比值比[OR]0.98,P<0.001)、体重指数(BMI)低(OR 0.95,P=0.002)以及复杂肺段切除术(OR 2.2,P<0.001)与PAL显著相关。
使用真实世界数据时,肺段切除术与PAL风险不可忽视,尤其是肺功能受损的患者以及复杂肺段切除术后的患者。这一发现有助于指导决策过程。