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尼日利亚东南部一家教学医院中患者对直接督导下的短程化疗肺结核治疗策略的遵从性。

Compliance of patients to DOTS tuberculosis treatment strategy in a South-East Nigeria Teaching Hospital.

机构信息

Department of Community Medicine, University of Nigeria, Enugu.

UNICEF Field Office, Enugu, Nigeria.

出版信息

Afr Health Sci. 2022 Sep;22(3):599-606. doi: 10.4314/ahs.v22i3.64.

DOI:10.4314/ahs.v22i3.64
PMID:36910349
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9993299/
Abstract

INTRODUCTION

Tuberculosis ranks the second highest cause of adult mortality after HIV in the world. The Directly Observed Treatment Short course (DOTS) strategy is aimed at following up on patients' adherence to treatment regimen.

OBJECTIVES

To assess the level of compliance of patients to the DOTS strategy.

MATERIALS AND METHODS

A retrospective study of patients seen at the University of Nigeria Teaching Hospital from January, 2013 to April, 2015. Relevant information was collected from patients' folders. Data analysis was with the SPSS and results represented in tables.

RESULTS

111 (50%) patients were compliant with their DOTS treatment plan while 107 (41.3%) were non-compliant. Ninety-two patients (41.4%) were successfully treated and discharged home, 7 patients (3.2%) referred to other centres. The proportion of patients regarding their marital status, occupation, educational level and address that was compliant to the DOTS TB reflected varied patterns.

CONCLUSION/ RECOMMENDATIONS: The study reflected poor to average compliance to DOTS. There is a need for creation of more DOTS centres; regular surveys and updates on DOTS TB strategy should be the norm rather than the exception.

摘要

简介

结核病是世界上继艾滋病之后导致成年人死亡的第二大病因。直接观察治疗短期疗程(DOTS)策略旨在监测患者对治疗方案的遵守情况。

目的

评估患者对 DOTS 策略的遵守程度。

材料和方法

这是一项回顾性研究,研究对象为 2013 年 1 月至 2015 年 4 月在尼日利亚大学教学医院就诊的患者。从患者的文件夹中收集相关信息。使用 SPSS 进行数据分析,结果以表格形式呈现。

结果

111 名(50%)患者遵守了他们的 DOTS 治疗计划,而 107 名(41.3%)患者不遵守。92 名患者(41.4%)成功接受治疗并出院回家,7 名患者(3.2%)被转介到其他中心。关于婚姻状况、职业、教育程度和住址等方面的患者遵守 DOTS 结核病的比例呈现出不同的模式。

结论/建议:该研究反映出 DOTS 的遵守情况较差到一般。有必要建立更多的 DOTS 中心;定期进行 DOTS 结核病策略的调查和更新应该成为常态,而不是例外。

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本文引用的文献

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Tuberculosis: a review of current concepts and control programme in Nigeria.结核病:尼日利亚当前概念与防控计划综述
Niger J Med. 2011 Apr-Jun;20(2):200-6.
2
Compliance with tuberculosis treatment after the implementation of the directly observed treatment, short-course strategy in the city of Carapicuíba, Brazil.巴西卡拉皮库伊巴市实施直接观察短程化疗策略后对结核病治疗的遵从情况。
J Bras Pneumol. 2011 Mar-Apr;37(2):223-31. doi: 10.1590/s1806-37132011000200013.
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Factors influencing compliance in patients with tuberculosis on directly observed therapy at Ile-Ife, Nigeria.尼日利亚伊费地区接受直接观察治疗的肺结核患者治疗依从性的影响因素
East Afr Med J. 2000 May;77(5):235-9. doi: 10.4314/eamj.v77i5.46625.
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Factors affecting patient compliance with anti-tuberculosis chemotherapy using the directly observed treatment, short-course strategy (DOTS).采用直接观察治疗短程疗法(DOTS)时影响患者抗结核化疗依从性的因素。
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