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采用直接观察治疗短程疗法(DOTS)时影响患者抗结核化疗依从性的因素。

Factors affecting patient compliance with anti-tuberculosis chemotherapy using the directly observed treatment, short-course strategy (DOTS).

作者信息

O'Boyle S J, Power J J, Ibrahim M Y, Watson J P

机构信息

University of Leeds School of Medicine, UK.

出版信息

Int J Tuberc Lung Dis. 2002 Apr;6(4):307-12.

PMID:11936739
Abstract

SETTING

Kota Kinabalu and surrounding communities in Sabah, Malaysia.

OBJECTIVES

To establish factors affecting compliance of patients with anti-tuberculosis chemotherapy, their knowledge of the disease, and views on improving the DOTS strategy.

DESIGN

Interviews with compliant patients attending clinics for DOTS treatment and with non-compliant patients in their homes, in August and September 2000.

RESULTS

A total of 63 compliant and 23 non-compliant patients were interviewed. For non-compliant patients, reaching the treatment centre entailed greater cost (P < 0.005) and travel time (P < 0.005) compared to compliant patients. Cost of transport was the reason most frequently given for non-attendance. Non-compliant patients were more likely to have completed secondary education (P < 0.05), and to be working (P < 0.01). More non-compliant patients had family members who had had the disease (P < 0.01). There was no difference between the groups for overall tuberculosis knowledge scores; however, non-compliant patients were more likely to think that treatment could be stopped once they were symptom free (P < 0.01). Most patients (73%) felt that the DOTS system could be improved by provision of more information about tuberculosis.

CONCLUSION

Compliance with DOTS in the Kota Kinabalu area is affected by travel expenses, time spent travelling to treatment centres, and having family members who have had the disease. Patients would like more information on tuberculosis.

摘要

地点

马来西亚沙巴州哥打基纳巴卢及其周边社区。

目的

确定影响肺结核化疗患者依从性的因素、他们对该疾病的了解程度以及对改进直接观察治疗策略的看法。

设计

2000年8月和9月,对在直接观察治疗诊所就诊的依从性患者以及在家中的非依从性患者进行访谈。

结果

共访谈了63名依从性患者和23名非依从性患者。与依从性患者相比,非依从性患者前往治疗中心的费用更高(P<0.005),出行时间更长(P<0.005)。交通费用是最常被提及的未就诊原因。非依从性患者更有可能完成中等教育(P<0.05)且有工作(P<0.01)。更多非依从性患者有家庭成员患过该病(P<0.01)。两组的总体结核病知识得分无差异;然而,非依从性患者更有可能认为一旦无症状就可以停止治疗(P<0.01)。大多数患者(73%)认为通过提供更多关于结核病的信息可以改进直接观察治疗系统。

结论

哥打基纳巴卢地区的直接观察治疗依从性受到交通费用、前往治疗中心所花费的时间以及有家庭成员患过该病的影响。患者希望获得更多关于结核病的信息。

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