乌干达中症-重症 COVID-19 住院患者的曲霉菌特异性 IgM/IgG 抗体血清阳性率。
Aspergillus-specific IgM/IgG antibody serostatus of patients hospitalized with moderate-critical COVID-19 in Uganda.
机构信息
Department of Medical Microbiology and Immunology, Gulu University Medical School, Gulu Uganda.
Translational research laboratory, Department of Research, Infectious Diseases Institute, College of Health Sciences, Makerere University, P.O Box 22418, Kampala, Uganda.
出版信息
Afr Health Sci. 2022 Sep;22(3):506-511. doi: 10.4314/ahs.v22i3.54.
Abstract
Invasive pulmonary aspergillosis is known to complicate the coronavirus diseases-2019 (COVID-19), especially those with critical illness. We investigated the baseline anti-Aspergillus antibody serostatus of patients with moderate-critical COVID-19 hospitalized at 3 COVID-19 Treatment Units in Uganda. All 46 tested patients, mean age 30, and 11% with underlying respiratory disease had a negative serum anti-Aspergillus IgM/IgG antibody immunochromatographic test on day 3 (mean) of symptom onset (range 1-26), but follow up specimens to assess seroconversion were not available.
摘要
侵袭性肺曲霉病已知会使 2019 年冠状病毒病（COVID-19）复杂化，尤其是那些患有重症的患者。我们调查了乌干达 3 个 COVID-19 治疗单位中中度至重度 COVID-19 住院患者的基线抗曲霉抗体血清阳性率。所有 46 名接受检测的患者，平均年龄 30 岁，11%患有潜在呼吸道疾病，在症状出现第 3 天（平均）的血清抗曲霉 IgM/IgG 抗体免疫层析检测呈阴性（范围 1-26），但没有可用于评估血清转化的后续标本。
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