Cunha John-Lennon-Silva, Fraga Vitória-Ribeiro-Almico, de Lima Wliana-Pontes, Andrade Allany-de Oliveira, Gordón-Núñez Manuel-Antonio, Nonaka Cassiano-Francisco-Weege, Alves Pollianna-Muniz, Júnior Ricardo-Luiz-Cavalcanti-de Albuquerque
DDS, MSc, Professor. Department of Dentistry, State University of Paraíba (UEPB), Campina Grande, PB, Brazil.
DDS,MSc student Laboratory of Morphology and Experimental Pathology, Institute of Technology and Research, Tiradentes University (UNIT), Aracaju, SE, Brazil.
J Clin Exp Dent. 2023 Feb 1;15(2):e88-e95. doi: 10.4317/jced.59738. eCollection 2023 Feb.
The present study aimed to evaluate the clinicopathologic features of salivary gland tumors (SGTs) in a Brazillian northeast population.
A retrospective descriptive cross-sectional study was performed (1995-2009). All cases of SGTs diagnosed in a private surgical pathology service in Brazil were reviewed, and clinicopathological data were collected.
A total of 23.258 histopathological records of biopsies were analyzed, and 174 cases were diagnosed as SGTs (0.7%). Of these, 117 (67.2%) were classified as benign, and 57 (32.8%) were malignant. The series comprised 89 females (51.1%) and 85 males (48.9%), with a mean age of 50.2 years (range: 3-96 years) and a roughly equal female-to-male ratio (1:1). Most tumors occurred in the parotid gland (n = 82, 47.1%), followed by the palate (n = 45, 25.9%), submandibular gland (n = 15, 8.6%). Pleomorphic adenoma (n = 83; 70.9%) and mucoepidermoid carcinoma (n = 19, 33.3%) were the most frequent benign and malignant tumors, respectively. After reevaluation of morphology and immunohistochemical analysis, seven tumors (4.0%) were reclassified following the current WHO Classification of the Head and Neck Tumors.
The general features of SGT from the studied Brazilian population were similar to previously published reports in other countries. However, SGTs do not show any sex predilection. Although careful morphological analysis is the key to the correct diagnosis of these tumors, immunohistochemical analysis is essential to establish an accurate diagnosis in the face of challenging cases. Salivary gland tumors, epidemiology, head and neck pathology.
本研究旨在评估巴西东北部人群唾液腺肿瘤（SGTs）的临床病理特征。
进行了一项回顾性描述性横断面研究（1995 - 2009年）。对巴西一家私立外科病理服务机构诊断的所有SGTs病例进行了复查，并收集了临床病理数据。
共分析了23258份活检的组织病理学记录，其中174例被诊断为SGTs（0.7%）。其中，117例（67.2%）为良性，57例（32.8%）为恶性。该系列包括89名女性（51.1%）和85名男性（48.9%），平均年龄为50.2岁（范围：3 - 96岁），男女比例大致相等（1:1）。大多数肿瘤发生在腮腺（n = 82，47.1%），其次是腭部（n = 45，25.9%）、下颌下腺（n = 15，8.6%）。多形性腺瘤（n = 83；70.9%）和黏液表皮样癌（n = 19，33.3%）分别是最常见的良性和恶性肿瘤。在重新评估形态学和免疫组化分析后，根据当前世界卫生组织头颈部肿瘤分类，7例肿瘤（4.0%）被重新分类。
所研究的巴西人群中SGTs的一般特征与其他国家先前发表的报告相似。然而，SGTs没有显示出任何性别偏好。尽管仔细的形态学分析是正确诊断这些肿瘤的关键，但面对具有挑战性的病例时，免疫组化分析对于准确诊断至关重要。唾液腺肿瘤、流行病学、头颈部病理学。
