Reinheimer Angélica, Vieira Daniella-Serafin-Couto, Cordeiro Mabel-Mariela-Rodríguez, Rivero Elena-Riet-Correa
Postgraduate Program in Dentistry, Federal University of Santa Catarina, Florianópolis, SC, Brazil.
Department of Pathology, Federal University of Santa Catarina, Florianópolis, SC, Brazil.
J Clin Exp Dent. 2019 Nov 1;11(11):e1025-e1032. doi: 10.4317/jced.55685. eCollection 2019 Nov.
Salivary gland tumors are a rare and morphologically diverse group of lesions and their frequency is still unknown in several parts of the world. The knowledge of its population characteristics contributes to a better understanding of its etiopathogenesis. Objectives: This study investigated the frequency of salivary gland tumors in a region of southern Brazil and compared these data in a literature review.
A retrospective study was conducted of salivary gland tumors diagnosed at two pathology centers from 1995 to 2016. Patient age and gender, tumor site and frequency, histopathological diagnosis, and symptomatology were evaluated. Chi-squared tests were used to assess the associations between variables. To compare our data, we also conducted a literature review of publications in the PubMed and LILACS databases of retrospective studies of salivary gland tumors.
A total of 124 salivary gland tumor cases was identified, 81 (65.3%) of which were classified as benign and 43 (34.6%) as malignant. Most tumors occurred in the parotid gland (57.2%). Pleomorphic adenoma was the most common tumor (59.6%), followed by adenocarcinoma not otherwise specified (8.8%). The tumors occurred more often in women (54.8%) than in men (45.2%). Malignant tumors were associated with pain in 31.4% of cases (<0.05). The literature review included 35 articles from different countries. Women were most affected, with a mean age of 41.7 years. The most common benign tumor was pleomorphic adenoma (48.2%) and the most common malignant tumor was mucoepidermoid carcinoma (8.7%).
The results of the present study showed that salivary gland tumors are rare. The parotid gland is the most common location and pleomorphic adenoma are the most frequent lesions. The malignant tumors presented as several histological types and the incidence was variable globally. Salivary gland neoplasms, salivary gland diseases, oral surgery, epidemiology.
涎腺肿瘤是一组罕见且形态多样的病变，在世界上一些地区其发病率仍然未知。了解其人群特征有助于更好地理解其病因发病机制。目的：本研究调查巴西南部某地区涎腺肿瘤的发病率，并在文献综述中比较这些数据。
对1995年至2016年在两个病理中心诊断的涎腺肿瘤进行回顾性研究。评估患者的年龄和性别、肿瘤部位和发病率、组织病理学诊断以及症状。采用卡方检验评估变量之间的关联。为了比较我们的数据，我们还对PubMed和LILACS数据库中涎腺肿瘤回顾性研究的出版物进行了文献综述。
共确定124例涎腺肿瘤病例，其中81例（65.3%）为良性，43例（34.6%）为恶性。大多数肿瘤发生在腮腺（57.2%）。多形性腺瘤是最常见的肿瘤（59.6%），其次是未另行指定的腺癌（8.8%）。肿瘤在女性中发生的频率（54.8%）高于男性（45.2%）。31.4%的恶性肿瘤病例伴有疼痛（<0.05）。文献综述包括来自不同国家的35篇文章。女性受影响最大，平均年龄为41.7岁。最常见的良性肿瘤是多形性腺瘤（48.2%），最常见的恶性肿瘤是黏液表皮样癌（8.7%）。
本研究结果表明涎腺肿瘤较为罕见。腮腺是最常见的发病部位，多形性腺瘤是最常见的病变。恶性肿瘤呈现多种组织学类型，全球发病率各不相同。涎腺肿瘤、涎腺疾病、口腔外科、流行病学。
