Suzuki Shunji
Obstetrics and Gynecology, Japanese Red Cross Katsushika Maternity Hospital, Tokyo, JPN.
Cureus. 2023 Mar 7;15(3):e35875. doi: 10.7759/cureus.35875. eCollection 2023 Mar.
Objective We compared the recent obstetric outcomes of women aged 40 and over as advanced maternal age (AMA) to those with AMA more than 10 years ago. Methods This was a retrospective study of primiparous singleton pregnancies who delivered at ≥22 weeks of gestation managed at Japanese Red Cross Katsushika Maternity Hospital between 2003-2007 and 2013-2017. Results The percentage of primiparous women aged with AMA who delivered at ≥22 weeks of gestation increased from 1.5 to 4.8% (p<0.01) due to the increase in the pregnancy conceived by in vitro fertilization (IVF). In the pregnancies with AMA, the percentage of cesarean delivery decreased from 51.7 to 41.0% (p=0.01), while the prevalence of postpartum hemorrhage increased from 7.5 to 14.9% (p=0.01). The latter was associated with an increased rate of in vitro fertilization (IVF) use. Conclusions The percentage of AMA pregnancies significantly increased with the development of assisted reproductive technology, and the prevalence of postpartum hemorrhage also increased in AMA pregnancies.
我们将40岁及以上的高龄产妇（AMA）近期的产科结局与10多年前的高龄产妇进行了比较。方法：这是一项回顾性研究，研究对象为2003 - 2007年和2013 - 2017年在日本红十字会葛饰妇产医院分娩的孕周≥22周的初产单胎妊娠。结果：由于体外受精（IVF）受孕的增加，孕周≥22周分娩的高龄初产妇比例从1.5%增至4.8%（p<0.01）。在高龄产妇的妊娠中，剖宫产比例从51.7%降至41.0%（p = 0.01），而产后出血发生率从7.5%增至14.9%（p = 0.01）。后者与体外受精（IVF）使用率增加有关。结论：随着辅助生殖技术的发展，高龄产妇妊娠比例显著增加，高龄产妇妊娠中产后出血发生率也有所增加。
