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伴有模仿脓肿的咽后受累的儿童多系统炎症综合征（MIS-C）：阿那白滞素的治疗作用

Multi-System Inflammatory Syndrome in Children (MIS-C) with Retropharyngeal Involvement Mimicking Abscess: the Therapeutic Role of Anakinra.

作者信息

Troisi Angela, Accomando Francesco, Mambelli Lorenzo, Marchetti Federico

机构信息

Department of Pediatrics, Santa Maria delle Croci Hospital, 48121 Ravenna, Italy.

Specialty School of Pediatrics, Alma Mater Studiorum, Universita di Bologna, 40126 Bologna, Italy.

出版信息

Arch Clin Med Case Rep. 2023;7(1):80-81. doi: 10.26502/acmcr.96550577. Epub 2023 Feb 10.

DOI:10.26502/acmcr.96550577
PMID:36911808
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10004091/
Abstract

Multi-System Inflammatory Syndrome in Children (MIS-C) is a new diagnostic entity that appeared with the Covid-19 pandemic, and that only concerns the pediatric age. Early diagnosis and early immunomodulatory treatment lead most of the time to a complete resolution of the pathology. We present a case of MIS-C, whose main clinical feature was neck pain due to inflammation of retropharyngeal tissues. The use of anakinra was critical for healing.

摘要

儿童多系统炎症综合征（MIS-C）是一种在新冠疫情期间出现的新诊断实体，仅涉及儿童年龄段。早期诊断和早期免疫调节治疗大多时候可使病情完全缓解。我们报告一例MIS-C病例，其主要临床特征是因咽后组织炎症导致的颈部疼痛。使用阿那白滞素对治愈至关重要。

相似文献

1
Multi-System Inflammatory Syndrome in Children (MIS-C) with Retropharyngeal Involvement Mimicking Abscess: the Therapeutic Role of Anakinra.伴有模仿脓肿的咽后受累的儿童多系统炎症综合征（MIS-C）：阿那白滞素的治疗作用
Arch Clin Med Case Rep. 2023;7(1):80-81. doi: 10.26502/acmcr.96550577. Epub 2023 Feb 10.
2
Multisystem inflammatory syndrome in children associated with COVID-19 presenting as cervical inflammation.儿童多系统炎症综合征与 COVID-19 相关，表现为颈部炎症。
Acta Paediatr. 2023 Mar;112(3):477-482. doi: 10.1111/apa.16623. Epub 2022 Dec 20.
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Case Report: Use of Anakinra in Multisystem Inflammatory Syndrome During COVID-19 Pandemic.病例报告：在新冠疫情期间托珠单抗在多系统炎症综合征中的应用。 你提供的原文中药物名称有误，正确的应该是“Tocilizumab”（托珠单抗），而不是“Anakinra”。按照正确内容翻译如上。
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J Pediatr Surg Case Rep. 2021 Aug;71:101913. doi: 10.1016/j.epsc.2021.101913. Epub 2021 May 19.

本文引用的文献

1
American College of Rheumatology Clinical Guidance for Multisystem Inflammatory Syndrome in Children Associated With SARS-CoV-2 and Hyperinflammation in Pediatric COVID-19: Version 3.美国风湿病学会儿童 COVID-19 相关 SARS-CoV-2 与儿童多系统炎症综合征及过度炎症的临床指导：第 3 版
Arthritis Rheumatol. 2022 Apr;74(4):e1-e20. doi: 10.1002/art.42062. Epub 2022 Feb 3.
2
Retropharyngeal Edema and Neck Pain in Multisystem Inflammatory Syndrome in Children (MIS-c).儿童多系统炎症综合征（MIS-C）中的咽后水肿和颈部疼痛。
J Pediatric Infect Dis Soc. 2021 Oct 27;10(9):922-925. doi: 10.1093/jpids/piab050.
3
Multisystem inflammatory syndrome in children (MIS-C) and retropharyngeal edema: A case series.
儿童多系统炎症综合征（MIS-C）与咽后水肿：病例系列研究。
Int J Pediatr Otorhinolaryngol. 2021 May;144:110667. doi: 10.1016/j.ijporl.2021.110667. Epub 2021 Mar 4.
4
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Clin Rheumatol. 2021 May;40(5):2097-2098. doi: 10.1007/s10067-020-05538-x. Epub 2021 Jan 13.
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Eur J Pediatr. 2014 Mar;173(3):381-6. doi: 10.1007/s00431-013-2179-0. Epub 2013 Oct 22.
7
Retropharyngeal edema: an unusual manifestation of Kawasaki disease.咽后水肿：川崎病的一种不寻常表现。
J Emerg Med. 2010 Aug;39(2):181-5. doi: 10.1016/j.jemermed.2008.08.004. Epub 2009 Jan 15.